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MedKoo Cat#: 563080 | Name: alpha-RA-F

Description:

WARNING: This product is for research use only, not for human or veterinary use.

alpha-RA-F is a modulator of collagen synthesis and matrix metalloproteinases (MMPs) expression levels. It acts by boosting collagen synthesis and reducing MMPs expression levels in human fibroblasts without cytotoxicity.

Chemical Structure

alpha-RA-F
alpha-RA-F
CAS#1260239-23-3

Theoretical Analysis

MedKoo Cat#: 563080

Name: alpha-RA-F

CAS#: 1260239-23-3

Chemical Formula: C16H16N2O4

Exact Mass: 300.1110

Molecular Weight: 300.31

Elemental Analysis: C, 63.99; H, 5.37; N, 9.33; O, 21.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
alpha-RA-F; alpha RA F; alphaRAF; α-RA-F; α RA F; αRAF;
IUPAC/Chemical Name
(S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-3,5-dihydroxybenzamide
InChi Key
VIBGZWUSHYPKCT-AWEZNQCLSA-N
InChi Code
InChI=1S/C16H16N2O4/c17-15(21)14(6-10-4-2-1-3-5-10)18-16(22)11-7-12(19)9-13(20)8-11/h1-5,7-9,14,19-20H,6H2,(H2,17,21)(H,18,22)/t14-/m0/s1
SMILES Code
OC1=CC(C(N[C@H](C(N)=O)CC2=CC=CC=C2)=O)=CC(O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 300.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kwak SY, Noh JM, Lee S, Lee SH, Jeon SJ, Kim HI, Kim JH, Lee YS. Effect of alpha-resorcylic acid-L-phenylalanine amide on collagen synthesis and matrix metalloproteinase expression in fibroblasts. Bioorg Med Chem Lett. 2014 Feb 1;24(3):742-5. doi: 10.1016/j.bmcl.2013.12.110. Epub 2014 Jan 3. PubMed PMID: 24411126.