Synonym
Kelevan; Caswell No. 436C; Despirol;
IUPAC/Chemical Name
1,3,4-Metheno-1H-cyclobuta(cd)pentalene-2-pentanoic acid, 1,1a,3,3a,4,5,5,5a,5b,6-decachlorooctahydro-2-hydroxy-gamma-oxo-, ethyl ester
InChi Key
POSKOXIJDWDKPH-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H12Cl10O4/c1-2-31-7(29)4-3-6(28)5-8(30)9(18)11(20)13(22)10(8,19)14(23)12(9,21)15(11,24)17(26,27)16(13,14)25/h30H,2-5H2,1H3
SMILES Code
O=C(OCC)CCC(CC1(O)C2(Cl)C3(Cl)C4(Cl)C(Cl)(Cl)C5(Cl)C3(Cl)C1(Cl)C5(Cl)C24Cl)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
634.78
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Dabrowski J, St Waliszewski. [Methodological hints on the gas chromatographic determination of kelevan and kepone in potatoes, potato foliage and soil]. Nahrung. 1979;23(1):33-7. German. PubMed PMID: 89629.
2: George SE, Claxton LD. Biotransformation of chlordecone by Pseudomonas species. Xenobiotica. 1988 Apr;18(4):407-16. PubMed PMID: 2456645.
3: Maier-Bode H. The insecticide "Kelevan". Residue Rev. 1976;63:45-76. Review. PubMed PMID: 790503.
4: Styczyńska B, Krzemińska A, Mańkowska H, Sereda B. [Kelevan used as poisoned nutrition in the destruction of Pharaoh's ants (Monomorium pharaonis L.)]. Rocz Panstw Zakl Hig. 1976;27(5):577-85. Polish. PubMed PMID: 981893.
5: Epstein SS. Kepone--hazard evaluation. Sci Total Environ. 1978 Jan;9(1):1-62. Review. PubMed PMID: 74851.
6: Glukhova LG. [Changes in blood enzyme activity and electrolyte composition under successive effects of ethanol and organochlorine pesticides]. Gig Sanit. 1991 Feb;(2):58-9. Russian. PubMed PMID: 2055516.
7: Benigni R, Bignami M, Camoni I, Carere A, Conti G, Iachetta R, Morpurgo G, Ortali VA. A new in vitro method for testing plant metabolism in mutagenicity studies. J Toxicol Environ Health. 1979 Sep;5(5):809-19. PubMed PMID: 513148.
8: Boreĭko NR. [Effect of the pesticide, despirol, on the internal organ morphology of experimental animals]. Gig Sanit. 1980 Dec;(12):68-9. Russian. PubMed PMID: 7203079.
9: Jaszczuk E, Syrowatka T. [Mutagenic effect of various pesticides on Salmonella typhimurium]. Rocz Panstw Zakl Hig. 1980;31(3):305-11. Polish. PubMed PMID: 6774408.
10: LeVan KE, Hung KL, McCann KR, Ludka JT, Holway DA. Floral visitation by the Argentine ant reduces pollinator visitation and seed set in the coast barrel cactus, Ferocactus viridescens. Oecologia. 2014 Jan;174(1):163-71. doi: 10.1007/s00442-013-2739-z. Epub 2013 Jul 28. PubMed PMID: 23892582.
