Glutamyl ribose 5-phosphate | CAS#89026-42-6 | bioacive chemical

MedKoo Cat#: 597109 | Name: Glutamyl ribose 5-phosphate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Glutamyl ribose 5-phosphate is isolated from the linkage region in ADP ribosylation of proteins.

Chemical Structure

Glutamyl ribose 5-phosphate

CAS#89026-42-6

Theoretical Analysis

MedKoo Cat#: 597109

Name: Glutamyl ribose 5-phosphate

CAS#: 89026-42-6

Chemical Formula: C10H18NO11P

Exact Mass: 359.0617

Molecular Weight: 359.22

Elemental Analysis: C, 33.44; H, 5.05; N, 3.90; O, 48.99; P, 8.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Glutamyl ribose 5-phosphate; Glu-R-S-P;

IUPAC/Chemical Name

(2S)-2-amino-5-(((3R,4S,5R)-3,4-dihydroxy-5-((phosphonooxy)methyl)tetrahydrofuran-2-yl)oxy)-5-oxopentanoic acid

InChi Key

OLGLUECQOANCCO-IDXQGAQYSA-N

InChi Code

InChI=1S/C10H18NO11P/c11-4(9(15)16)1-2-6(12)22-10-8(14)7(13)5(21-10)3-20-23(17,18)19/h4-5,7-8,10,13-14H,1-3,11H2,(H,15,16)(H2,17,18,19)/t4-,5+,7+,8+,10?/m0/s1

SMILES Code

N[C@@H](CCC(OC1[C@@H]([C@@H]([C@@H](COP(O)(O)=O)O1)O)O)=O)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 359.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Williams JC, Verani R, Alcala H, Butler IJ, Rosenberg HS. Glutamyl ribose-5-phosphate storage disease: nephrotic syndrome and cerebral atrophy. Pediatr Pathol. 1986;5(3-4):277-94. PubMed PMID: 3786260. 2: Williams JC, Butler IJ, Rosenberg HS, Verani R, Scott CI, Conley SB. Progressive neurologic deterioration and renal failure due to storage of glutamyl ribose-5-phosphate. N Engl J Med. 1984 Jul 19;311(3):152-5. PubMed PMID: 6738601. 3: Williams JC, Chambers JP, Liehr JG. Glutamyl ribose 5-phosphate storage disease. A hereditary defect in the degradation of poly(ADP-ribosylated) proteins. J Biol Chem. 1984 Jan 25;259(2):1037-42. PubMed PMID: 6693374.