MedKoo Cat#: 591605 | Name: Phenyl salicylate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel. It is synthesized by heating salicylic acid with phenol.

Chemical Structure

Phenyl salicylate
Phenyl salicylate
CAS#118-55-8

Theoretical Analysis

MedKoo Cat#: 591605

Name: Phenyl salicylate

CAS#: 118-55-8

Chemical Formula: C13H10O3

Exact Mass: 214.0630

Molecular Weight: 214.22

Elemental Analysis: C, 72.89; H, 4.71; O, 22.41

Price and Availability

Size Price Availability Quantity
50g USD 230.00
250g USD 340.00
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Related CAS #
No Data
Synonym
Phenyl salicylate; NSC 33406; NSC-33406; NSC33406
IUPAC/Chemical Name
Phenyl salicylate
InChi Key
ZQBAKBUEJOMQEX-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
SMILES Code
OC1=CC=CC=C1C(OC2=CC=CC=C2)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
Phenyl salicylate, or salol, is a chemical substance, introduced in 1886 by Marceli Nencki of Basel.
In vitro activity:
The polylactic acid composite films were successfully fabricated via the technique of solvent casting using cellulose acetate (20%, wt) as the reinforcing material and phenyl salicylate as the ultraviolet (UV) absorbent and antibacterial agent. Polylactic acid-cellulose acetate-phenyl salicylate composite films displayed complete absorption effect at the region of UV-C (280-100 nm) and UV-B (315-280 nm), and more than 95% UV absorption effect at the region of UV-A (400-315 nm). These results indicate that the UV shielding performance of the composite films could be significantly improve by addition of phenyl salicylate. Reference: Int J Biol Macromol. 2022 Jun 30;211:85-93. https://pubmed.ncbi.nlm.nih.gov/35561857/
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 214.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
1. Liang L, Chen H. Development and characterization of biodegradable ultraviolet protective and antibacterial polylactic acid-cellulose acetate film modified by phenyl salicylate. Int J Biol Macromol. 2022 Jun 30;211:85-93. doi: 10.1016/j.ijbiomac.2022.05.055. Epub 2022 May 10. PMID: 35561857. 2. Fagge II, Khalid K, Noh MAM, Yusof NSM, Zain SM, Khan MN. Study of Cationic and Nonionic Mixed Micelles with NaBr and 3,5-Cl2C6H3CO2Na by Use of Probe Nucleophilic Reaction of Piperidine with Ionized Phenyl Salicylate. J Oleo Sci. 2018 Jan 1;67(1):55-66. doi: 10.5650/jos.ess17033. Epub 2017 Dec 14. PMID: 29238023.
In vitro protocol:
1. Liang L, Chen H. Development and characterization of biodegradable ultraviolet protective and antibacterial polylactic acid-cellulose acetate film modified by phenyl salicylate. Int J Biol Macromol. 2022 Jun 30;211:85-93. doi: 10.1016/j.ijbiomac.2022.05.055. Epub 2022 May 10. PMID: 35561857. 2. Fagge II, Khalid K, Noh MAM, Yusof NSM, Zain SM, Khan MN. Study of Cationic and Nonionic Mixed Micelles with NaBr and 3,5-Cl2C6H3CO2Na by Use of Probe Nucleophilic Reaction of Piperidine with Ionized Phenyl Salicylate. J Oleo Sci. 2018 Jan 1;67(1):55-66. doi: 10.5650/jos.ess17033. Epub 2017 Dec 14. PMID: 29238023.
In vivo protocol:
TBD