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MedKoo Cat#: 558180 | Name: Fenhexamid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fenhexamid is an antifungal agent (pesticides) used for agriculture, and is present at measurable amounts in fruits and vegetables.

Chemical Structure

Fenhexamid
Fenhexamid
CAS#126833-17-8

Theoretical Analysis

MedKoo Cat#: 558180

Name: Fenhexamid

CAS#: 126833-17-8

Chemical Formula: C14H17Cl2NO2

Exact Mass: 301.0600

Molecular Weight: 302.19

Elemental Analysis: C, 55.64; H, 5.67; Cl, 23.46; N, 4.64; O, 10.59

Price and Availability

Size Price Availability Quantity
250mg USD 250.00 2 Weeks
1g USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
Fenhexamid; Teldor; Elevate; KBR2738; KBR 2738; KBR-2738
IUPAC/Chemical Name
Cyclohexanecarboxamide, N-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-
InChi Key
VDLGAVXLJYLFDH-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H17Cl2NO2/c1-14(7-3-2-4-8-14)13(19)17-9-5-6-10(18)12(16)11(9)15/h5-6,18H,2-4,7-8H2,1H3,(H,17,19)
SMILES Code
O=C(C1(C)CCCCC1)NC2=CC=C(O)C(Cl)=C2Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 302.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Go RE, Kim CW, Choi KC. Effect of fenhexamid and cyprodinil on the expression of cell cycle- and metastasis-related genes via an estrogen receptor-dependent pathway in cellular and xenografted ovarian cancer models. Toxicol Appl Pharmacol. 2015 Nov 15;289(1):48-57. doi: 10.1016/j.taap.2015.09.001. Epub 2015 Sep 5. PubMed PMID: 26344002. 2: Teng Y, Manavalan TT, Hu C, Medjakovic S, Jungbauer A, Klinge CM. Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicol Sci. 2013 Jan;131(1):71-83. doi: 10.1093/toxsci/kfs290. Epub 2012 Oct 10. PubMed PMID: 23052036; PubMed Central PMCID: PMC3537134. 3: Debieu D, Bach J, Montesinos E, Fillinger S, Leroux P. Role of sterol 3-ketoreductase sensitivity in susceptibility to the fungicide fenhexamid in Botrytis cinerea and other phytopathogenic fungi. Pest Manag Sci. 2013 May;69(5):642-51. doi: 10.1002/ps.3418. Epub 2012 Nov 9. PubMed PMID: 23139232. 4: Mofeed J, Mosleh YY. Toxic responses and antioxidative enzymes activity of Scenedesmus obliquus exposed to fenhexamid and atrazine, alone and in mixture. Ecotoxicol Environ Saf. 2013 Sep;95:234-40. doi: 10.1016/j.ecoenv.2013.05.023. Epub 2013 Jun 22. PubMed PMID: 23796667. 5: Nagel DA, Hill EJ, O'Neil J, Mireur A, Coleman MD. The effects of the fungicides fenhexamid and myclobutanil on SH-SY5Y and U-251 MG human cell lines. Environ Toxicol Pharmacol. 2014 Nov;38(3):968-76. doi: 10.1016/j.etap.2014.09.005. Epub 2014 Sep 16. PubMed PMID: 25461557. 6: Lénárt J, Bujna E, Kovács B, Békefi E, Száraz L, Dernovics M. Metabolomic approach assisted high resolution LC-ESI-MS based identification of a xenobiotic derivative of fenhexamid produced by Lactobacillus casei. J Agric Food Chem. 2013 Sep 18;61(37):8969-75. doi: 10.1021/jf4022493. Epub 2013 Sep 6. PubMed PMID: 23971653. 7: Cardenas-Flores A, Cranenbrouck S, Draye X, Guillet A, Govaerts B, Declerck S. The sterol biosynthesis inhibitor molecule fenhexamid impacts the vegetative compatibility of Glomus clarum. Mycorrhiza. 2011 Jul;21(5):443-449. doi: 10.1007/s00572-011-0385-z. Epub 2011 May 7. PubMed PMID: 21553021. 8: Yin D, Wu S, Liu N, Yin Y, Ma Z. The natural fenhexamid-resistant grey mould populations from strawberry in Zhejiang Province are dominated by Botrytis cinerea group S. Pest Manag Sci. 2016 Aug;72(8):1540-8. doi: 10.1002/ps.4183. Epub 2015 Dec 18. PubMed PMID: 26537826. 9: Angioni A, Porcu L, Dedola F. Determination of famoxadone, fenamidone, fenhexamid and iprodione residues in greenhouse tomatoes. Pest Manag Sci. 2012 Apr;68(4):543-7. doi: 10.1002/ps.2287. Epub 2011 Nov 18. PubMed PMID: 22102420. 10: Billard A, Fillinger S, Leroux P, Lachaise H, Beffa R, Debieu D. Strong resistance to the fungicide fenhexamid entails a fitness cost in Botrytis cinerea, as shown by comparisons of isogenic strains. Pest Manag Sci. 2012 May;68(5):684-91. doi: 10.1002/ps.2312. Epub 2011 Nov 2. PubMed PMID: 22045588. 11: Maheswari MA, Lamshöft M, Sukul P, Spiteller P, Zühlke S, Spiteller M. Photochemical analysis of 14C-fenhexamid in aqueous solution and structural elucidation of a new metabolite. Chemosphere. 2010 Nov;81(7):844-52. doi: 10.1016/j.chemosphere.2010.08.013. PubMed PMID: 20804999. 12: Fillinger S, Leroux P, Auclair C, Barreau C, Al Hajj C, Debieu D. Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea. Antimicrob Agents Chemother. 2008 Nov;52(11):3933-40. doi: 10.1128/AAC.00615-08. Epub 2008 Sep 8. PubMed PMID: 18779358; PubMed Central PMCID: PMC2573126. 13: Zocco D, Van Aarle IM, Oger E, Lanfranco L, Declerck S. Fenpropimorph and fenhexamid impact phosphorus translocation by arbuscular mycorrhizal fungi. Mycorrhiza. 2011 Jul;21(5):363-374. doi: 10.1007/s00572-010-0344-0. Epub 2010 Nov 18. PubMed PMID: 21085999. 14: Christensen HB, Granby K, Rabølle M. Processing factors and variability of pyrimethanil, fenhexamid and tolylfluanid in strawberries. Food Addit Contam. 2003 Aug;20(8):728-41. PubMed PMID: 13129790. 15: Campagnac E, Lounès-Hadj Sahraoui A, Debiane D, Fontaine J, Laruelle F, Garçon G, Verdin A, Durand R, Shirali P, Grandmougin-Ferjani A. Arbuscular mycorrhiza partially protect chicory roots against oxidative stress induced by two fungicides, fenpropimorph and fenhexamid. Mycorrhiza. 2010 Mar;20(3):167-78. doi: 10.1007/s00572-009-0267-9. Epub 2009 Sep 16. PubMed PMID: 19756779. 16: Mercader JV, Abad-Fuentes A. Monoclonal antibody generation and direct competitive enzyme-linked immunosorbent assay evaluation for the analysis of the fungicide fenhexamid in must and wine. J Agric Food Chem. 2009 Jun 24;57(12):5129-35. doi: 10.1021/jf900867u. PubMed PMID: 19530708. 17: Baglieri A, Borzí D, Abbate C, Négre M, Gennari M. Removal of fenhexamid and pyrimethanil from aqueous solutions by clays and organoclays. J Environ Sci Health B. 2009 Mar;44(3):220-5. doi: 10.1080/03601230902728153. PubMed PMID: 19280474. 18: Hem L, Choi JH, Park JH, Mamun MI, Cho SK, Abd El-Aty AM, Shim JH. Residual pattern of fenhexamid on pepper fruits grown under greenhouse conditions using HPLC and confirmation via tandem mass spectrometry. Food Chem. 2011 Jun 15;126(4):1533-8. doi: 10.1016/j.foodchem.2010.11.147. Epub 2010 Dec 9. PubMed PMID: 25213923. 19: Angioni A, Schirra M, Garau VL, Melis M, Tuberoso CI, Cabras P. Residues of azoxystrobin, fenhexamid and pyrimethanil in strawberry following field treatments and the effect of domestic washing. Food Addit Contam. 2004 Nov;21(11):1065-70. PubMed PMID: 15764335. 20: Lambropoulou DA, Konstantinou IK, Albanis TA, Fernández-Alba AR. Photocatalytic degradation of the fungicide Fenhexamid in aqueous TiO(2) suspensions: identification of intermediates products and reaction pathways. Chemosphere. 2011 Apr;83(3):367-78. doi: 10.1016/j.chemosphere.2010.12.006. Epub 2010 Dec 30. PubMed PMID: 21194726.