Synonym
Propaphos; Kayaphos; Kayphosnac;
IUPAC/Chemical Name
Phosphoric acid, 4-(methylthio)phenyl dipropyl ester (9CI)
InChi Key
PWYIUEFFPNVCMW-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H21O4PS/c1-4-10-15-18(14,16-11-5-2)17-12-6-8-13(19-3)9-7-12/h6-9H,4-5,10-11H2,1-3H3
SMILES Code
O=P(OCCC)(OCCC)OC1=CC=C(SC)C=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
304.34
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Yamada S, Okudaira H, Hayashi E. An alteration in sensitivity to cholinergic agents on guinea-pig ilea and atria after repeated administration of an organophosphate and an antagonism by a carbamate. Arch Int Pharmacodyn Ther. 1979 Sep;241(1):32-44. PubMed PMID: 526070.
2: Nagayama M, Akahori F, Chiwata H, Shirai M, Motoya M, Masaoka T, Sakaguchi K. Effects of selected organophosphate insecticides on serum cholinesterase isoenzyme patterns in the rat. Vet Hum Toxicol. 1996 Jun;38(3):196-9. PubMed PMID: 8727219.
3: Sakaguchi K, Nagayama M, Masaoka T, Nishimura A, Kageyama K, Shirai M, Akahori F. Effects of fenthion, isoxathion, dichlorvos and propaphos on the serum cholinesterase isoenzyme patterns of dogs. Vet Hum Toxicol. 1997 Feb;39(1):1-5. PubMed PMID: 9004458.
4: Yamada S, Katsuoka M, Okudaira H, Hayashi E. A pharmacological comparison of organophosphorus and carbamate anti-cholinesterase agents on guinea pig ileum. Toxicol Appl Pharmacol. 1982 Jun 15;64(1):79-87. PubMed PMID: 7112587.
5: Okudaira H, Matsui S, Hayashi S, Yamada S, Isogai M, Shinozuka K, Hayashi E. [Toxicity and general pharmacological effects of 4-methylthiophenyl dipropyl phosphate]. Yakugaku Zasshi. 1984 Apr;104(4):374-83. Japanese. PubMed PMID: 6491875.
