MedKoo Cat#: 563037 | Name: AHR-activator-1023

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AHR-activator-1023 is an activator of the aryl hydrocarbon receptor (AHR).It is also a specific modulator of FGF2-induced branching morphogenesis.

Chemical Structure

AHR-activator-1023
AHR-activator-1023
CAS#352346-46-4

Theoretical Analysis

MedKoo Cat#: 563037

Name: AHR-activator-1023

CAS#: 352346-46-4

Chemical Formula: C14H8Cl2N2O

Exact Mass: 290.0014

Molecular Weight: 291.13

Elemental Analysis: C, 57.76; H, 2.77; Cl, 24.35; N, 9.62; O, 5.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
AHR-activator-1023; AHR activator 1023; Branching Morphogenesis Modulator 1023; BMM 1023; Compound 1023; Cpd 1023;
IUPAC/Chemical Name
5-(2,4-Dichloro-phenyl)-3-phenyl-[1,2,4]oxadiazole
InChi Key
WMJVJVBCUBCALD-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H8Cl2N2O/c15-10-6-7-11(12(16)8-10)14-17-13(18-19-14)9-4-2-1-3-5-9/h1-8H
SMILES Code
ClC1=CC=C(C2=NC(C3=CC=CC=C3)=NO2)C(Cl)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Basham KJ, Kieffer C, Shelton DN, Leonard CJ, Bhonde VR, Vankayalapati H, Milash B, Bearss DJ, Looper RE, Welm BE. Chemical genetic screen reveals a role for desmosomal adhesion in mammary branching morphogenesis. J Biol Chem. 2013 Jan 25;288(4):2261-70. doi: 10.1074/jbc.M112.411033. Epub 2012 Dec 3. PubMed PMID: 23212921; PubMed Central PMCID: PMC3554898.