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MedKoo Cat#: 597054 | Name: L-Neopterin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L-Neopterin is a cholinergic receptor.

Chemical Structure

L-Neopterin
L-Neopterin
CAS#2277-43-2

Theoretical Analysis

MedKoo Cat#: 597054

Name: L-Neopterin

CAS#: 2277-43-2

Chemical Formula: C9H11N5O4

Exact Mass: 253.0811

Molecular Weight: 253.21

Elemental Analysis: C, 42.69; H, 4.38; N, 27.66; O, 25.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Neopterin, L-erythro-; L-Neopterin; Neopterin, L-(-)-; L-Erythro-neopterin;
IUPAC/Chemical Name
2-amino-6-((1R,2S)-1,2,3-trihydroxypropyl)pteridin-4(1H)-one
InChi Key
BMQYVXCPAOLZOK-UJURSFKZSA-N
InChi Code
InChI=1S/C9H11N5O4/c10-9-13-7-5(8(18)14-9)12-3(1-11-7)6(17)4(16)2-15/h1,4,6,15-17H,2H2,(H3,10,11,13,14,18)/t4-,6+/m0/s1
SMILES Code
O=C1N=C(N)NC2=NC=C([C@@H](O)[C@@H](O)CO)N=C12
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 253.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nomura T, Tazawa M, Ohtsuki M, Sumi-Ichinose C, Hagino Y, Ota A, Nakashima A, Mori K, Sugimoto T, Ueno O, Nozawa Y, Ichinose H, Nagatsu T. Enzymes related to catecholamine biosynthesis in Tetrahymena pyriformis. Presence of GTP cyclohydrolase I. Comp Biochem Physiol B Biochem Mol Biol. 1998 Aug;120(4):753-60. PubMed PMID: 9854821. 2: Tani Y, Ishihara T, Kanai T, Ohno T, Andersson J, Lilja A, Antoni G, Fasth KJ, Bjurling P, Westerberg G, et al. Effects of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin on the dopaminergic and cholinergic receptors as evaluated by positron emission tomography in the Rhesus monkey. J Neural Transm Gen Sect. 1995;102(3):189-208. PubMed PMID: 8788068. 3: Curtius HC, Matasovic A, Schoedon G, Kuster T, Guibaud P, Giudici T, Blau N. 7-Substituted pterins. A new class of mammalian pteridines. J Biol Chem. 1990 Mar 5;265(7):3923-30. PubMed PMID: 2303485. 4: Curtius HC, Kuster T, Matasovic A, Blau N, Dhondt JL. Primapterin, anapterin, and 6-oxo-primapterin, three new 7-substituted pterins identified in a patient with hyperphenylalaninemia. Biochem Biophys Res Commun. 1988 Jun 16;153(2):715-21. PubMed PMID: 3382399. 5: Kuster T, Matasović A, Niederwieser A. Application of gas chromatography-mass spectrometry to the study of biopterin metabolism in man. Detection of biolumazine and 2'-deoxysepialumazine. J Chromatogr. 1984 May 4;290:303-10. PubMed PMID: 6547448. 6: Niederwieser A, Blau N, Wang M, Joller P, Atarés M, Cardesa-Garcia J. GTP cyclohydrolase I deficiency, a new enzyme defect causing hyperphenylalaninemia with neopterin, biopterin, dopamine, and serotonin deficiencies and muscular hypotonia. Eur J Pediatr. 1984 Feb;141(4):208-14. PubMed PMID: 6734669. 7: Niederwieser A, Curtius HC, Bettoni O, Bieri J, Schircks B, Viscontini M, Schaub J. Atypical phenylketonuria caused by 7, 8-dihydrobiopterin synthetase deficiency. Lancet. 1979 Jan 20;1(8108):131-3. PubMed PMID: 84153. 8: Eto I, Fukushima K, Shiota T. Enzymatic synthesis of biopterin from D-erythrodihydroneopterin triphosphate by extracts of kidneys from Syrian golden hamsters. J Biol Chem. 1976 Nov 10;251(21):6505-12. PubMed PMID: 10299.