MedKoo Cat#: 563035 | Name: Dextropimaric acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dextropimaric acid is a shaker channel opener. It acts by inhibiting of TNF-α-induced MMP-9 production and HASMC migration via down-regulated NF-κB and AP-1.

Chemical Structure

Dextropimaric acid
Dextropimaric acid
CAS#127-27-5

Theoretical Analysis

MedKoo Cat#: 563035

Name: Dextropimaric acid

CAS#: 127-27-5

Chemical Formula: C20H30O2

Exact Mass: 302.2200

Molecular Weight: 302.45

Elemental Analysis: C, 79.42; H, 10.00; O, 10.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Dextropimaric acid; Pimaric acid; D-Pimaric acid; NSC-2956; NSC 2956; NSC2956; D Pimaric acid;
IUPAC/Chemical Name
(1R,4aR,4bS,7S,10aR)-7-Ethenyl-1,4a,7-trimethyl-3,4,4b,5,6,9,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid
InChi Key
MHVJRKBZMUDEEV-APQLOABGSA-N
InChi Code
InChI=1S/C20H30O2/c1-5-18(2)12-9-15-14(13-18)7-8-16-19(15,3)10-6-11-20(16,4)17(21)22/h5,13,15-16H,1,6-12H2,2-4H3,(H,21,22)/t15-,16+,18+,19+,20+/m0/s1
SMILES Code
O=C([C@]1(C)CCC[C@]2(C)[C@@]3([H])CC[C@@](C)(C=C)C=C3CC[C@@]12[H])O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 302.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: HARRIS GC, SANDERSON TF. Resin acids; the position of the ring double bond in dextropimaric acid and the structure of isodextropimaric acid. J Am Chem Soc. 1948 Jun;70(6):2081-5. PubMed PMID: 18863802. 2: HARRIS GC, SANDERSON TF. Resin acids; the isolation of dextropimaric acid and a new pimaric-type acid, isodextropimaric acid. J Am Chem Soc. 1948 Jun;70(6):2079-81. PubMed PMID: 18863801.