MedKoo Cat#: 597034 | Name: Cydrin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chemical Structure

Cydrin
Cydrin
CAS#53317-25-2

Theoretical Analysis

MedKoo Cat#: 597034

Name: Cydrin

CAS#: 53317-25-2

Chemical Formula: C14H32Br2Cl4N6O2S22

Exact Mass:

Molecular Weight: 682.17

Elemental Analysis: C, 24.65; H, 4.73; Br, 23.43; Cl, 20.79; N, 12.32; O, 4.69; S, 9.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Cydrin;
IUPAC/Chemical Name
Cystine, bis(N,N-2-chloroethyl)hydrazide, dihydrobromide, L-
InChi Key
HMYZDKRQBPHONL-AQEKLAMFSA-P
InChi Code
InChI=1S/C14H28Cl4N6O2S2.2BrH/c15-1-5-23(6-2-16)21-13(25)11(19)9-27-28-10-12(20)14(26)22-24(7-3-17)8-4-18;;/h11-12H,1-10,19-20H2,(H,21,25)(H,22,26);2*1H/p+2/t11-,12-;;/m0../s1
SMILES Code
ClCCN(CCCl)NC([C@@H]([NH3+])CSSC[C@H]([NH3+])C(NN(CCCl)CCCl)=O)=O.Br.Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 682.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Saha A, Johansen T, Hedeholm R, Nielsen EE, Westgaard JI, Hauser L, Planque B, Cadrin SX, Boje J. Geographic extent of introgression in Sebastes mentella and its effect on genetic population structure. Evol Appl. 2016 Oct 22;10(1):77-90. doi: 10.1111/eva.12429. eCollection 2017 Jan. PubMed PMID: 28035237; PubMed Central PMCID: PMC5192944. 2: Smith LA, Link JS, Cadrin SX, Palka DL. Consumption by marine mammals on the Northeast U.S. continental shelf. Ecol Appl. 2015 Mar;25(2):373-89. PubMed PMID: 26263661. 3: Chaillet N, Dumont A, Abrahamowicz M, Pasquier JC, Audibert F, Monnier P, Abenhaim HA, Dubé E, Dugas M, Burne R, Fraser WD; QUARISMA Trial Research Group. A cluster-randomized trial to reduce cesarean delivery rates in Quebec. N Engl J Med. 2015 Apr 30;372(18):1710-21. doi: 10.1056/NEJMoa1407120. PubMed PMID: 25923551. 4: Fortier AM, Asselin E, Cadrin M. Keratin 8 and 18 loss in epithelial cancer cells increases collective cell migration and cisplatin sensitivity through claudin1 up-regulation. J Biol Chem. 2013 Apr 19;288(16):11555-71. doi: 10.1074/jbc.M112.428920. Epub 2013 Feb 28. PubMed PMID: 23449973; PubMed Central PMCID: PMC3630871. 5: Fortier AM, Asselin E, Cadrin M. Functional specificity of Akt isoforms in cancer progression. Biomol Concepts. 2011 Apr 1;2(1-2):1-11. doi: 10.1515/bmc.2011.003. PubMed PMID: 25962016. 6: Fortier AM, Riopel K, Désaulniers M, Cadrin M. Novel insights into changes in biochemical properties of keratins 8 and 18 in griseofulvin-induced toxic liver injury. Exp Mol Pathol. 2010 Oct;89(2):117-25. doi: 10.1016/j.yexmp.2010.07.004. Epub 2010 Jul 17. PubMed PMID: 20643122. 7: Kerr LA, Cadrin SX, Secor DH. The role of spatial dynamics in the stability, resilience, and productivity of an estuarine fish population. Ecol Appl. 2010 Mar;20(2):497-507. PubMed PMID: 20405802. 8: Fortier AM, Van Themsche C, Asselin E, Cadrin M. Akt isoforms regulate intermediate filament protein levels in epithelial carcinoma cells. FEBS Lett. 2010 Mar 5;584(5):984-8. doi: 10.1016/j.febslet.2010.01.045. Epub 2010 Jan 28. PubMed PMID: 20109457. 9: Zatloukal K, French SW, Stumptner C, Strnad P, Harada M, Toivola DM, Cadrin M, Omary MB. From Mallory to Mallory-Denk bodies: what, how and why? Exp Cell Res. 2007 Jun 10;313(10):2033-49. Epub 2007 Apr 27. Review. PubMed PMID: 17531973. 10: Zhou Q, Cadrin M, Herrmann H, Chen CH, Chalkley RJ, Burlingame AL, Omary MB. Keratin 20 serine 13 phosphorylation is a stress and intestinal goblet cell marker. J Biol Chem. 2006 Jun 16;281(24):16453-61. Epub 2006 Apr 10. PubMed PMID: 16608857. 11: Fausther M, Villeneuve L, Cadrin M. Heat shock protein 70 expression, keratin phosphorylation and Mallory body formation in hepatocytes from griseofulvin-intoxicated mice. Comp Hepatol. 2004 Aug 12;3(1):5. PubMed PMID: 15307891; PubMed Central PMCID: PMC516018. 12: Alméras N, Després JP, Villeneuve J, Demers MF, Roy MA, Cadrin C, Mottard JP, Bouchard RH. Development of an atherogenic metabolic risk factor profile associated with the use of atypical antipsychotics. J Clin Psychiatry. 2004 Apr;65(4):557-64. PubMed PMID: 15119921. 13: Satoh MI, Hovington H, Cadrin M. Reduction of cytochemical ecto-ATPase activities in keratin 8-deficient FVB/N mouse livers. Med Electron Microsc. 1999 Dec;32(4):209-212. PubMed PMID: 11810447. 14: Bouchard RH, Demers MF, Simoneau I, Alméras N, Villeneuve J, Mottard JP, Cadrin C, Lemieux I, Després JP. Atypical antipsychotics and cardiovascular risk in schizophrenic patients. J Clin Psychopharmacol. 2001 Feb;21(1):110-1. PubMed PMID: 11199934. 15: Cadrin M, Hovington H, Marceau N, McFarlane-Anderson N. Early perturbations in keratin and actin gene expression and fibrillar organisation in griseofulvin-fed mouse liver. J Hepatol. 2000 Aug;33(2):199-207. PubMed PMID: 10952237. 16: Levine D, Goldstein RB, Cadrin C. Distention of the fetal duodenum: abnormal finding? J Ultrasound Med. 1998 Apr;17(4):213-5. PubMed PMID: 9544603. 17: Bégin-Heick N, Black MA, Gaffield J, Cadrin M. Subcellular localization of G-proteins in primary-cultured mouse preadipocytes and adipocytes. J Cell Biochem. 1997 May;65(2):259-66. PubMed PMID: 9136083. 18: Cadrin M, McFarlane-Anderson N, Harper ME, Gaffield J, Bégin-Heick N. Comparison of the subcellular distribution of G-proteins in hepatocytes in situ and in primary cultures. J Cell Biochem. 1996 Sep 1;62(3):334-41. PubMed PMID: 8872605. 19: Cadrin M, Martinoli MG. Alterations of intermediate filaments in various histopathological conditions. Biochem Cell Biol. 1995 Sep-Oct;73(9-10):627-34. Review. PubMed PMID: 8714682. 20: Cadrin M, Anderson NM, Aasheim LH, Kawahara H, Franks DJ, French SW. Modifications in cytokeratin and actin in cultured liver cells derived from griseofulvin-fed mice. Lab Invest. 1995 Apr;72(4):453-60. PubMed PMID: 7536860.