Quintozene | CAS#82-68-8 | pesticide

MedKoo Cat#: 591566 | Name: Quintozene

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Quintozene, also known as pentachloronitrobenzene, is used as a soil fungicide on lawns and ornamental crops, as a seed treatment of field crops and vegetables, and as a slime inhibitor in industrial waters. It is no longer approved for use within the European Union.

Chemical Structure

Quintozene

CAS#82-68-8

Theoretical Analysis

MedKoo Cat#: 591566

Name: Quintozene

CAS#: 82-68-8

Chemical Formula: C6Cl5NO2

Exact Mass: 292.8372

Molecular Weight: 295.32

Elemental Analysis: C, 24.40; Cl, 60.02; N, 4.74; O, 10.83

Price and Availability

Size	Price	Availability	Quantity
100g	USD 260.00	2 weeks

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Synonym

Quintozene; NSC 58427; NSC-58427; NSC58427, Pentachloronitrobenzene

IUPAC/Chemical Name

Benzene, 1,2,3,4,5-pentachloro-6-nitro-

InChi Key

LKPLKUMXSAEKID-UHFFFAOYSA-N

InChi Code

InChI=1S/C6Cl5NO2/c7-1-2(8)4(10)6(12(13)14)5(11)3(1)9

SMILES Code

O=[N+](C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1Cl)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in Toluene, Methanol, and Heptane

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

Quintozene is a C-nitro compound, a member of pentachlorobenzenes and an aromatic fungicide.

In vitro activity:

This study investigated the in vitro activity of four anthelmintics, four chemical fungicides and two antifungal drugs on the spore germination of nematophagous fungi. The results showed that 10 tested drugs, except for levamisole and quintozene, had in vitro inhibitory effects on nematophagous fungi. Reference: Lett Appl Microbiol. 2021 Aug;73(2):124-131. https://pubmed.ncbi.nlm.nih.gov/33590540/

In vivo activity:

Influences of nanoparticles on the accumulation of pesticides in terrestrial organisms are still unclear. This study investigated the influences and mechanisms of metal oxide nanoparticles on accumulation of quintozene in earthworms. Results showed that changes biomarkers demonstrated that pollutants injured earthworms. This study provides a novel hypothesis that nanoparticles facilitate organic pollutants entering terrestrial organisms, and that nanoparticles can exacerbate environmental risks of other pollutants. Reference: Environ Sci Pollut Res Int. 2021 Oct;28(37):51471-51479. https://pubmed.ncbi.nlm.nih.gov/33983610/

	Solvent	mg/mL	mM
Solubility
	Toulene	1,140.0	3,860.22
	Methanol	20.0	67.72
	Heptane	30.0	101.58

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 295.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

1. Xuan Z, Ma Y, Zhang J, Zhu J, Cai M. Dissolved legacy and emerging organochlorine pesticides in the Antarctic marginal seas: Occurrence, sources and transport. Mar Pollut Bull. 2023 Feb;187:114511. doi: 10.1016/j.marpolbul.2022.114511. Epub 2022 Dec 27. PMID: 36580836. 2. Wang B, Zhang N, Gong P, Li J, Wang X, Li X, Wang F, Cai K, Zhang X. In vitro assays on the susceptibility of four species of nematophagous fungi to anthelmintics and chemical fungicides/antifungal drug. Lett Appl Microbiol. 2021 Aug;73(2):124-131. doi: 10.1111/lam.13462. Epub 2021 Jun 15. PMID: 33590540. 3. Li M, Xu G, Guo N, Zheng N, Dong W, Li X, Yu Y. Influences and mechanisms of nanoparticles on pentachloronitrobenzene accumulation by earthworms. Environ Sci Pollut Res Int. 2021 Oct;28(37):51471-51479. doi: 10.1007/s11356-021-14368-6. Epub 2021 May 13. PMID: 33983610. 4. To-Figueras J, Gómez-Catalán J, Rodamilans M, Corbella J. Studies on sex differences in excretion of sulphur derivatives of hexachlorobenzene and pentachloronitrobenzene by rats. Toxicol Lett. 1991 Apr;56(1-2):87-94. doi: 10.1016/0378-4274(91)90093-l. PMID: 2017788.

In vitro protocol:

In vivo protocol:

1. Li M, Xu G, Guo N, Zheng N, Dong W, Li X, Yu Y. Influences and mechanisms of nanoparticles on pentachloronitrobenzene accumulation by earthworms. Environ Sci Pollut Res Int. 2021 Oct;28(37):51471-51479. doi: 10.1007/s11356-021-14368-6. Epub 2021 May 13. PMID: 33983610. 2. To-Figueras J, Gómez-Catalán J, Rodamilans M, Corbella J. Studies on sex differences in excretion of sulphur derivatives of hexachlorobenzene and pentachloronitrobenzene by rats. Toxicol Lett. 1991 Apr;56(1-2):87-94. doi: 10.1016/0378-4274(91)90093-l. PMID: 2017788.

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