Synonym
Insect repellent M 3535; Insect repellent M 3535; Insect repellent M 3535
IUPAC/Chemical Name
Ethyl N-acetyl-N-butyl-beta-alaninate
InChi Key
VZRKEAFHFMSHCD-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H21NO3/c1-4-6-8-12(10(3)13)9-7-11(14)15-5-2/h4-9H2,1-3H3
SMILES Code
O=C(OCC)CCN(C(C)=O)CCCC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
215.29
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: von Elert E, Preuss K, Fink P. Infodisruption of inducible anti-predator defenses through commercial insect repellents? Environ Pollut. 2016 Mar;210:18-26. doi: 10.1016/j.envpol.2015.11.032. Epub 2015 Dec 18. PubMed PMID: 26708758.
2: Büchel K, Bendin J, Gharbi A, Rahlenbeck S, Dautel H. Repellent efficacy of DEET, Icaridin, and EBAAP against Ixodes ricinus and Ixodes scapularis nymphs (Acari, Ixodidae). Ticks Tick Borne Dis. 2015 Jun;6(4):494-8. doi: 10.1016/j.ttbdis.2015.03.019. Epub 2015 Apr 30. PubMed PMID: 25936273.
3: Xu P, Choo YM, De La Rosa A, Leal WS. Mosquito odorant receptor for DEET and methyl jasmonate. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16592-7. doi: 10.1073/pnas.1417244111. Epub 2014 Oct 27. PubMed PMID: 25349401; PubMed Central PMCID: PMC4246313.
4: Mottaleb MA, Usenko S, O'Donnell JG, Ramirez AJ, Brooks BW, Chambliss CK. Gas chromatography-mass spectrometry screening methods for select UV filters, synthetic musks, alkylphenols, an antimicrobial agent, and an insect repellent in fish. J Chromatogr A. 2009 Jan 30;1216(5):815-23. doi: 10.1016/j.chroma.2008.11.072. Epub 2008 Dec 3. PubMed PMID: 19100555.
5: McMahon C, Kröber T, Guerin PM. In vitro assays for repellents and deterrents for ticks: differing effects of products when tested with attractant or arrestment stimuli. Med Vet Entomol. 2003 Dec;17(4):370-8. PubMed PMID: 14651650.
6: Thavara U, Tawatsin A, Chompoosri J, Suwonkerd W, Chansang UR, Asavadachanukorn P. Laboratory and field evaluations of the insect repellent 3535 (ethyl butylacetylaminopropionate) and deet against mosquito vectors in Thailand. J Am Mosq Control Assoc. 2001 Sep;17(3):190-5. PubMed PMID: 14529087.
7: Teal JJ. Insect repellents and mosquito bites. N Engl J Med. 2002 Nov 21;347(21):1719-21; author reply 1719-21. PubMed PMID: 12444193.
8: Fradin MS, Day JF. Comparative efficacy of insect repellents against mosquito bites. N Engl J Med. 2002 Jul 4;347(1):13-8. PubMed PMID: 12097535.
9: Staub D, Debrunner M, Amsler L, Steffen R. Effectiveness of a repellent containing DEET and EBAAP for preventing tick bites. Wilderness Environ Med. 2002 Spring;13(1):12-20. PubMed PMID: 11929056.
10: Holzer RB. [Protection against biting mosquitoes]. Ther Umsch. 2001 Jun;58(6):341-6. Review. German. PubMed PMID: 11441693.
11: Sixl W, Sixl-Voigt B, Köck M. [Testing of industrial repellents against gnats and horseflies]. Geogr Med Suppl. 1989;2:61-4. German. PubMed PMID: 2501157.
