MedKoo Cat#: 563029 | Name: ERDRP-0519
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ERDRP-0519 is an orally available polymerase inhibitor. It shows efficacy against a lethal morbillivirus infection in a large animal model.

Chemical Structure

ERDRP-0519
ERDRP-0519
CAS#1374006-96-8

Theoretical Analysis

MedKoo Cat#: 563029

Name: ERDRP-0519

CAS#: 1374006-96-8

Chemical Formula: C23H30F3N5O4S

Exact Mass: 529.1971

Molecular Weight: 529.57

Elemental Analysis: C, 52.16; H, 5.71; F, 10.76; N, 13.22; O, 12.08; S, 6.05

Price and Availability

Size Price Availability Quantity
100mg USD 2,650.00 2 Weeks
200mg USD 3,650.00 2 Weeks
500mg USD 5,650.00 2 Weeks
1g USD 9,650.00 2 Weeks
2g USD 14,950.00 2 Weeks
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Synonym
ERDRP-0519; ERDRP 0519; ERDRP0519;
IUPAC/Chemical Name
1-Methyl-N-[4-[[(2S)-2-[2-(4-morpholinyl)ethyl]-1-piperidinyl]sulfonyl]phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
InChi Key
JVZHTUQIMBYDSX-SFHVURJKSA-N
InChi Code
InChI=1S/C23H30F3N5O4S/c1-29-20(16-21(28-29)23(24,25)26)22(32)27-17-5-7-19(8-6-17)36(33,34)31-10-3-2-4-18(31)9-11-30-12-14-35-15-13-30/h5-8,16,18H,2-4,9-15H2,1H3,(H,27,32)/t18-/m0/s1
SMILES Code
O=C(C1=CC(C(F)(F)F)=NN1C)NC2=CC=C(S(=O)(N3[C@H](CCN4CCOCC4)CCCC3)=O)C=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 529.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK. An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model. Sci Transl Med. 2014 Apr 16;6(232):232ra52. doi: 10.1126/scitranslmed.3008517. PubMed PMID: 24739760; PubMed Central PMCID: PMC4080709.