MedKoo Cat#: 563028 | Name: SOMG-833 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

SOMG-833 HCl is a selective c-MET inhibitor that acts by blocking c-MET dependent neoplastic effects and exerting antitumor activity.

Chemical Structure

SOMG-833 HCl
SOMG-833 HCl
CAS#1268264-10-3

Theoretical Analysis

MedKoo Cat#: 563028

Name: SOMG-833 HCl

CAS#: 1268264-10-3

Chemical Formula: C22H23ClF3N5O2

Exact Mass: 481.1492

Molecular Weight: 481.90

Elemental Analysis: C, 54.83; H, 4.81; Cl, 7.36; F, 11.83; N, 14.53; O, 6.64

Price and Availability

Size Price Availability Quantity
5mg USD 335.00 2 Weeks
10mg USD 555.00 2 Weeks
25mg USD 1,010.00 2 Weeks
50mg USD 1,600.00 2 Weeks
100mg USD 2,495.00 2 Weeks
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Synonym
SOMG-833 HCl; SOMG 833 HCl; SOMG833 HCl; SOMG-833 Hydrochloride; SOMG833 Hydrochloride; SOMG 833 Hydrochloride; Zgwatinib Hydrochloride; Zgwatinib HCl;
IUPAC/Chemical Name
[3-(4-Methyl-piperazin-1-yl)-7-trifluoromethyl-quinolin-5-yl]-(3-nitro-benzyl)-amine Hydrochloride
InChi Key
GVCODABMZBTSTD-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H22F3N5O2.ClH/c1-28-5-7-29(8-6-28)18-12-19-20(10-16(22(23,24)25)11-21(19)27-14-18)26-13-15-3-2-4-17(9-15)30(31)32;/h2-4,9-12,14,26H,5-8,13H2,1H3;1H
SMILES Code
O=[N+](C1=CC(CNC2=C3C=C(N4CCN(C)CC4)C=NC3=CC(C(F)(F)F)=C2)=CC=C1)[O-].[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 481.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhang HT, Wang L, Ai J, Chen Y, He CX, Ji YC, Huang M, Yang JY, Zhang A, Ding J, Geng MY. SOMG-833, a novel selective c-MET inhibitor, blocks c-MET-dependent neoplastic effects and exerts antitumor activity. J Pharmacol Exp Ther. 2014 Jul;350(1):36-45. doi: 10.1124/jpet.114.214817. Epub 2014 Apr 16. PMID: 24741075.