Synonym
CHEC-9; CHEC 9; CHEC9;
IUPAC/Chemical Name
(2R,5S,8S,11S,14S,17S,20S)-20-((S)-2-((R)-2-amino-3-mercaptopropanamido)-3-(1H-imidazol-4-yl)propanamido)-5-(3-amino-3-oxopropyl)-14-(hydroxymethyl)-2-(mercaptomethyl)-8,11,17-trimethyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazatricosanedioic acid
InChi Key
NECLVMNXEDDNTI-NZQCIUDGSA-N
InChi Code
1S/C34H54N12O14S2/c1-14(26(51)39-15(2)27(52)42-19(4-6-24(36)48)31(56)46-23(12-62)34(59)60)41-33(58)22(10-47)45-28(53)16(3)40-30(55)20(5-7-25(49)50)43-32(57)21(8-17-9-37-13-38-17)44-29(54)18(35)11-61/h9,13-16,18-23,47,61-62H,4-8,10-12,35H2,1-3H3,(H2,36,48)(H,37,38)(H,39,51)(H,40,55)(H,41,58)(H,42,52)(H,43,57)(H,44,54)(H,45,53)(H,46,56)(H,49,50)(H,59,60)/t14-,15-,16-,18-,19-,20-,21-,22-,23-/m0/s1
SMILES Code
C[C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CS)=O)Cc1nc[nH]c1)=O)CCC(O)=O)=O)C)=O)CO)=O)C)=O)C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CCC(N)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Patent license information:
Medkoo obtained license below patents form Drexel University
1. Small survival-promoting/immunomodulatory peptide for treatment of brain damage, neurodegenerative disorders, and inflammatory disorders United States issued patent 7,528,112
2. Small survival-promoting/immunomodulatory peptide for treatment of brain damage, neurodegenerative disorders, and inflammatory disorders United States issued patent 8,716,223
3. CHEC-7 a novel sPLA2 inhibitor United States issued patent 8,106,019
