Synonym
Conotoxin GII; alpha-Conotoxin G II;
IUPAC/Chemical Name
(S)-4-amino-5-(((3S,6R,12S,15S,18S,21S,24R,29R,32S,37aS,40R)-15,32-bis((1H-imidazol-5-yl)methyl)-12-(4-aminobutyl)-18-benzyl-24-carbamoyl-21-(hydroxymethyl)-3-methyl-1,4,7,10,13,16,19,22,30,33,39-undecaoxotetratriacontahydro-1H-29,6-(epiminopropanodithiomethano)pyrrolo[2,1-b1][1,2]dithia[5,8,11,14,17,20,23,26,29,32]decaazacyclopentatriacontin-40-yl)amino)-5-oxopentanoic acid
InChi Key
GBQKLTZKGNZVHO-PVGVDLJESA-N
InChi Code
1S/C57H81N19O16S4/c1-29-47(82)73-40-24-94-96-25-41(74-48(83)33(59)12-13-45(79)80)55(90)75-42(54(89)70-37(18-32-20-62-28-65-32)57(92)76-15-7-11-43(76)56(91)66-29)26-95-93-23-39(46(60)81)72-53(88)38(22-77)71-51(86)35(16-30-8-3-2-4-9-30)68-52(87)36(17-31-19-61-27-64-31)69-50(85)34(10-5-6-14-58)67-44(78)21-63-49(40)84/h2-4,8-9,19-20,27-29,33-43,77H,5-7,10-18,21-26,58-59H2,1H3,(H2,60,81)(H,61,64)(H,62,65)(H,63,84)(H,66,91)(H,67,78)(H,68,87)(H,69,85)(H,70,89)(H,71,86)(H,72,88)(H,73,82)(H,74,83)(H,75,90)(H,79,80)/t29-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-/m0/s1
SMILES Code
C[C@@H](C(N[C@H]1CSSC[C@H](NC([C@@H](N)CCC(O)=O)=O)C(N[C@@H](CSSC[C@@H](C(N)=O)NC([C@H](CO)NC([C@H](Cc2ccccc2)NC([C@@H](NC([C@H](CCCCN)NC(CNC1=O)=O)=O)Cc3cnc[nH]3)=O)=O)=O)C(N4)=O)=O)=O)NC([C@H](CCC5)N5C([C@@H]4Cc6[nH]cnc6)=O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
