Synonym
AHR-2666; AHR 2666; AHR2666
IUPAC/Chemical Name
1-Pyrrolidinecarboxamide, 3-(3-chlorophenoxy)-N-methyl-
InChi Key
NBWFTBLPNAIEQP-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H15ClN2O2/c1-14-12(16)15-6-5-11(8-15)17-10-4-2-3-9(13)7-10/h2-4,7,11H,5-6,8H2,1H3,(H,14,16)
SMILES Code
O=C(N1CC(OC2=CC=CC(Cl)=C2)CC1)NC
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
254.71
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Reder RF, Miura DS, Danilo P Jr, Rosen MR. The electrophysiological properties of normal neonatal and adult canine cardiac Purkinje fibers. Circ Res. 1981 May;48(5):658-68. PubMed PMID: 7214674.
2: Mary-Rabine L, Hordof AJ, Danilo P Jr, Malm JR, Rosen MR. Mechanisms for impulse initiation in isolated human atrial fibers. Circ Res. 1980 Aug;47(2):267-77. PubMed PMID: 7397958.
3: Rosen MR, Danilo P Jr. Effects of tetrodotoxin, lidocaine, verapamil, and AHR-2666 on Ouabain-induced delayed afterdepolarizations in canine Purkinje fibers. Circ Res. 1980 Jan;46(1):117-24. PubMed PMID: 7349912.
4: Siegal MS, Gliklich JI, Mary-Rabine L, Hoffman BF. Effects of AHR-2666 on electrical activity of canine cardiac tissues: possible inhibition of slow inward current. J Pharmacol Exp Ther. 1979 Dec;211(3):606-14. PubMed PMID: 512920.
5: Rosen MR, Reder RF, Hordof AJ, Davies M, Danilo P Jr. Age-related changes in Purkinje fiber action potentials of adult dogs. Circ Res. 1978 Dec;43(6):931-8. PubMed PMID: 709754.
6: Lustig KC, Kirsten EB. The site of action of AHR-2666 in frog sartorius muscle. J Pharmacol Exp Ther. 1974 Oct;191(1):156-63. PubMed PMID: 4547606.
