MedKoo Cat#: 596943 | Name: Capaurine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Capaurine is an alkaloid isolated from root tubers of Stephania kwangsiensis H.S. Lo.

Chemical Structure

Capaurine
Capaurine
CAS#478-14-8

Theoretical Analysis

MedKoo Cat#: 596943

Name: Capaurine

CAS#: 478-14-8

Chemical Formula: C21H25NO5

Exact Mass: 371.1733

Molecular Weight: 371.43

Elemental Analysis: C, 67.91; H, 6.78; N, 3.77; O, 21.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Capaurine; (-)-Capaurine; NSC 404532; NSC-404532; NSC404532;
IUPAC/Chemical Name
(S)-2,3,9,10-tetramethoxy-5,8,13,13a-tetrahydro-6H-isoquinolino[3,2-a]isoquinolin-1-ol
InChi Key
GSPIMPLJQOCBFY-HNNXBMFYSA-N
InChi Code
InChI=1S/C21H25NO5/c1-24-16-6-5-12-9-15-18-13(10-17(25-2)21(27-4)19(18)23)7-8-22(15)11-14(12)20(16)26-3/h5-6,10,15,23H,7-9,11H2,1-4H3/t15-/m0/s1
SMILES Code
OC1=C2C(CCN3CC4=C(OC)C(OC)=CC=C4C[C@]32[H])=CC(OC)=C1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 371.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zuo AX, Li L, Ma YS, Rao GX. [Akaloids from roots of Stephania dentifolia]. Zhongguo Zhong Yao Za Zhi. 2013 Feb;38(4):574-7. Chinese. PubMed PMID: 23713286. 2: Galan A, Cervero F, Laird JM. Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain. Brain Res Mol Brain Res. 2003 Aug 19;116(1-2):126-34. PubMed PMID: 12941468. 3: Min ZD, Zhong SM. [Studies on the alkaloids of Stephania kwangsiensis H. S. Lo (author's transl)]. Yao Xue Xue Bao. 1980 Sep;15(9):532-7. Chinese. PubMed PMID: 7234425. 4: Shimanouchi H, Sasada Y, Ihara M, Kametani T. The crystal structure of capaurine hydrobromide. Acta Crystallogr B. 1969 Jul 15;25(7):1310-9. PubMed PMID: 5819640. 5: Kametani T, Ihara M, Fukumoto K, Yagi H. Structural determination of capaurimine and capaurine. Tetrahedron Lett. 1968 Aug;(40):4251-4. PubMed PMID: 5671794.