MedKoo Cat#: 558102 | Name: Polynoxylin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Polynoxylin is an antiseptic for local treatment of the skin and the mouth.

Chemical Structure

Polynoxylin
Polynoxylin
CAS#9011-05-6

Theoretical Analysis

MedKoo Cat#: 558102

Name: Polynoxylin

CAS#: 9011-05-6

Chemical Formula: C2H6N2O2

Exact Mass: 90.0400

Molecular Weight: 90.08

Elemental Analysis: C, 26.67; H, 6.71; N, 31.10; O, 35.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Urea, polymer with formaldehyde; Formaldehyde, urea polymer; Gabrite; HSDB 7203; Hygromull;
IUPAC/Chemical Name
Poly(methi(bis(hydroxymethyl))ureylene)amer
InChi Key
ODGAOXROABLFNM-UHFFFAOYSA-N
InChi Code
InChI=1S/CH4N2O.CH2O/c2-1(3)4;1-2/h(H4,2,3,4);1H2
SMILES Code
NC(N)=O.C=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 90.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Blenkharn JI. Biological activity of polynoxylin--an insoluble urea-formaldehyde condensation product. J Clin Hosp Pharm. 1985 Dec;10(4):367-72. PubMed PMID: 4093507. 2: ALEXANDER JO. Polynoxylin (Anaflex) in dermatology. Br J Dermatol. 1962 Oct;74:364-71. PubMed PMID: 14011960. 3: Smith J. Comparing Sorbsan and polynoxylin/Melolin dressings after toenail removal. J Wound Care. 1992 Sep 2;1(3):17-19. PubMed PMID: 27911183. 4: Phillips HI. Treatment of denture stomatitis with polynoxylin. A double-blind trial. Br Dent J. 1970 Jan 20;128(2):78-80. PubMed PMID: 4914199. 5: HALER D. POLYNOXYLIN: A NEW ANTISEPTIC. Br J Clin Pract. 1964 May;18:267-70. PubMed PMID: 14147732. 6: Kingston D. Release of formaldehyde from polynoxylin and noxythiolin. J Clin Pathol. 1965 Sep;18(5):666-7. PubMed PMID: 5835451; PubMed Central PMCID: PMC473043. 7: Robbs J. The clinical evaluation of polynoxylin as an aerosol in the prevention of wound sepsis. Br J Clin Pract. 1972 Mar;26(3):127-8. PubMed PMID: 5046820. 8: HALER D. Polynoxylin. Nature. 1963 Apr 27;198:400-1. PubMed PMID: 13952075. 9: Pegum JM, Fegan WG. Polynoxylin in the treatment of varicose ulcers. Ir J Med Sci. 1968 Jul;7(7):299-302. PubMed PMID: 5678440. 10: Wernsdorfer G, Wernsdorfer WH. [Observations on the antibacterial effect of polyoxymethyleneurea (polynoxylin) in vitro]. Arzneimittelforschung. 1967 Sep;17(9):1204-7. German. PubMed PMID: 4971132. 11: el-Charkawi H, el-Said EA, Safouh HM, el-Raghi N. Effect of addition antimicrobial agents to denture reliners. Egypt Dent J. 1994 Jul;40(3):785-90. PubMed PMID: 9588157. 12: Lynch MJ, MacDermott JP, Byrne DJ, Stewart PA. Use of an antibacterial powder spray to prevent post prostatectomy urinary infection. J R Soc Med. 1991 Nov;84(11):667-8. PubMed PMID: 1744874; PubMed Central PMCID: PMC1295471. 13: TOMASINI C. [Clinical experience with the topical use of a new preparation derived from the polycondensation of urea and formaldehyde (Anaflex)]. G Ital Dermatol. 1962 Jan-Feb;103:56-61. Italian. PubMed PMID: 13921703.