Histidine | CAS#71-00-1 | amino acid

MedKoo Cat#: 596933 | Name: Histidine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Histidine is an essential amino acid that is required for the production of HISTAMINE.

Chemical Structure

Histidine

CAS#71-00-1

Theoretical Analysis

MedKoo Cat#: 596933

Name: Histidine

CAS#: 71-00-1

Chemical Formula: C6H9N3O2

Exact Mass: 155.0695

Molecular Weight: 155.15

Elemental Analysis: C, 46.45; H, 5.85; N, 27.08; O, 20.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Histidine; NSC 137773; NSC-137773; NSC137773; L-Histidine;

IUPAC/Chemical Name

L-histidine

InChi Key

HNDVDQJCIGZPNO-YFKPBYRVSA-N

InChi Code

InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

SMILES Code

N[C@@H](CC1=CNC=N1)C(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 155.15 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dastidar P, Sarkar K. A Cu(II) coordination polymer based exfoliated nano-sheet inhibits α-chymotrypsin. Chemistry. 2018 Jun 11. doi: 10.1002/chem.201802376. [Epub ahead of print] PubMed PMID: 29888818. 2: Choudhary KS, Mih N, Monk J, Kavvas E, Yurkovich JT, Sakoulas G, Palsson BO. The Staphylococcus aureus Two-Component System AgrAC Displays Four Distinct Genomic Arrangements That Delineate Genomic Virulence Factor Signatures. Front Microbiol. 2018 May 25;9:1082. doi: 10.3389/fmicb.2018.01082. eCollection 2018. PubMed PMID: 29887846; PubMed Central PMCID: PMC5981134. 3: Shin DS, Heo GI, Son SH, Oh CS, Lee YK, Cha JS. Development of an Improved Loop-Mediated Isothermal Amplification Assay for On-Site Diagnosis of Fire Blight in Apple and Pear. Plant Pathol J. 2018 Jun;34(3):191-198. doi: 10.5423/PPJ.FT.03.2018.0055. Epub 2018 Jun 1. PubMed PMID: 29887775; PubMed Central PMCID: PMC5985645. 4: Wang F, Shi H, Wang S, Wang Y, Cao Z, Li S. Amino acid metabolism in dairy cows and their regulation in milk synthesis. Curr Drug Metab. 2018 Jun 10. doi: 10.2174/1389200219666180611084014. [Epub ahead of print] PubMed PMID: 29886827. 5: Gomes SQ, Vitoriano L, de Arruda EGR, Ruiz ALTG, Candido T, de Carvalho JE, Lustri WR, Abbehausen C. Linear gold(I) complex with tris-(2-carboxyethyl)phosphine (TCEP): Selective antitumor activity and inertness toward sulfur proteins. J Inorg Biochem. 2018 Apr 14;186:104-115. doi: 10.1016/j.jinorgbio.2018.04.005. [Epub ahead of print] PubMed PMID: 29885553. 6: Verma L, Agrawal D, Jain NS. Enhanced central histaminergic transmission attenuates compulsive-like behavior in mice. Neuropharmacology. 2018 May 25;138:106-117. doi: 10.1016/j.neuropharm.2018.05.031. [Epub ahead of print] PubMed PMID: 29885535. 7: Tumhom S, Krusong K, Kidokoro SI, Katoh E, Pongsawasdi P. Significance of H461 at subsite +1 in substrate binding and transglucosylation activity of amylomaltase from Corynebacterium glutamicum. Arch Biochem Biophys. 2018 Jun 6. pii: S0003-9861(18)30333-3. doi: 10.1016/j.abb.2018.06.002. [Epub ahead of print] PubMed PMID: 29885290. 8: Dalrymple U, Arambepola R, Gething PW, Cameron E. How long do rapid diagnostic tests remain positive after anti-malarial treatment? Malar J. 2018 Jun 8;17(1):228. doi: 10.1186/s12936-018-2371-9. PubMed PMID: 29884184. 9: Juang YC, Fradera X, Han Y, Partridge AW. Repurposing a Histamine Detection Platform for High-Throughput Screening of Histidine Decarboxylase. SLAS Discov. 2018 Jun 1:2472555218778053. doi: 10.1177/2472555218778053. [Epub ahead of print] PubMed PMID: 29884090. 10: Piñas GE, Reinoso-Vizcaino NM, Yandar Barahona NY, Cortes PR, Duran R, Badapanda C, Rathore A, Bichara DR, Cian MB, Olivero NB, Perez DR, Echenique J. Crosstalk between the serine/threonine kinase StkP and the response regulator ComE controls the stress response and intracellular survival of Streptococcus pneumoniae. PLoS Pathog. 2018 Jun 8;14(6):e1007118. doi: 10.1371/journal.ppat.1007118. [Epub ahead of print] PubMed PMID: 29883472. 11: Xu B, Zhu Y, Wang CH, Qiu C, Sun J, Yan Y, Chen X, Wang JC, Zhang Q. Improved Cell Transfection of siRNA by pH-Responsive Nanomicelles Self-assembled with mPEG-b-PHis-b-PEI Copolymers. ACS Appl Mater Interfaces. 2018 Jun 8. doi: 10.1021/acsami.8b04301. [Epub ahead of print] PubMed PMID: 29882640. 12: Raynes JK, Domigan LJ, Pearce FG, Gerrard JA. Immobilisation of tobacco etch virus (TEV) protease on a high surface area protein nanofibril scaffold. Biotechnol Prog. 2018 Jun 7. doi: 10.1002/btpr.2670. [Epub ahead of print] PubMed PMID: 29882251. 13: Gu Z, Cao Z. Molecular switch-modulated fluorescent copper nanoclusters for selective and sensitive detection of histidine and cysteine. Anal Bioanal Chem. 2018 Jun 7. doi: 10.1007/s00216-018-1149-9. [Epub ahead of print] PubMed PMID: 29882076. 14: Alfano M, Pérard J, Miras R, Catty P, Cavazza C. Biophysical and structural characterization of the putative nickel chaperone CooT from Carboxydothermus hydrogenoformans. J Biol Inorg Chem. 2018 Jun 7. doi: 10.1007/s00775-018-1576-2. [Epub ahead of print] PubMed PMID: 29882029. 15: Foreman DJ, Betancourt SK, Pilo AL, McLuckey SA. Novel Peptide Ion Chemistry Associated with Gold (I) Cationization: Preferential Cleavage at Lysine Residues. Int J Mass Spectrom. 2018 Apr;427:114-122. doi: 10.1016/j.ijms.2017.11.011. Epub 2017 Nov 21. PubMed PMID: 29881326; PubMed Central PMCID: PMC5985815. 16: Ding S, Abudupataer M, Zhou Z, Chen J, Li H, Xu L, Zhang W, Zhang S, Zou Y, Hong T, Wang TC, Yang X, Ge J. Histamine deficiency aggravates cardiac injury through miR-206/216b-Atg13 axis-mediated autophagic-dependant apoptosis. Cell Death Dis. 2018 Jun 7;9(6):694. doi: 10.1038/s41419-018-0723-6. PubMed PMID: 29880830; PubMed Central PMCID: PMC5992227. 17: McDougall M, McEleney K, Francisco O, Trieu B, Ogbomo EK, Tomy G, Stetefeld J. Reductive power of the archaea right-handed coiled coil nanotube (RHCC-NT) and incorporation of mercury clusters inside protein cages. J Struct Biol. 2018 Jun 5. pii: S1047-8477(18)30137-0. doi: 10.1016/j.jsb.2018.05.013. [Epub ahead of print] PubMed PMID: 29879486. 18: Watanabe Y, Kobayashi I, Ohnaka T, Watanabe S. In vitro synthesis of phospholipids with yeast phospholipase B, a phospholipid deacylating enzyme. Biotechnol Rep (Amst). 2018 Apr 4;18:e00250. doi: 10.1016/j.btre.2018.e00250. eCollection 2018 Jun. PubMed PMID: 29876301; PubMed Central PMCID: PMC5989593. 19: Keum C, Lee SY. Iridium-coordinated Histidyl Bolaamphiphile Self-assemblies as Heterogeneous Catalysts for Water Oxidation. ChemSusChem. 2018 Jun 6. doi: 10.1002/cssc.201800461. [Epub ahead of print] PubMed PMID: 29873890. 20: Kitamura A, Shibasaki A, Takeda K, Suno R, Kinjo M. Analysis of the substrate recognition state of TDP-43 to single-stranded DNA using fluorescence correlation spectroscopy. Biochem Biophys Rep. 2018 Apr 12;14:58-63. doi: 10.1016/j.bbrep.2018.03.009. eCollection 2018 Jul. PubMed PMID: 29872735; PubMed Central PMCID: PMC5986658.