Aromadendrene | CAS#14682-34-9 | Diverse sesquiterpene

MedKoo Cat#: 559060 | Name: Aromadendrene

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aromadendrene is a sesquiterpene that has been found in E. globulus and has diverse biological activities. It is active against various strains of methicillin-resistant S. aureus (MRSA) and vancomycin-resistant enterococci (VRE; MICs = 0.25-1 mg/ml). Aromadendrene (1 mM) inhibits tert-butyl hydroperoxide-induced formation of thiobarbituric acid reactive substances (TBARS) in isolated rat liver hepatocytes. It inhibits the proliferation of HepG2 liver and PC3 prostate cancer cells (IC50s = 20 and 9.3 µM, respectively).

Chemical Structure

Aromadendrene

CAS#14682-34-9

Theoretical Analysis

MedKoo Cat#: 559060

Name: Aromadendrene

CAS#: 14682-34-9

Chemical Formula: C15H24

Exact Mass: 204.1878

Molecular Weight: 204.35

Elemental Analysis: C, 88.16; H, 11.84

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Related CAS #

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Synonym

l-Aromadendrene; Aromadendrene, (-)-; beta-Diploalbicene; (-)-10(14)-Aromadendrene; (+)-Aromadendrene;

IUPAC/Chemical Name

(1aS,4aS,7S,7aS,7bR)-1,1,7-trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulene

InChi Key

ITYNGVSTWVVPIC-NDKCEZKHSA-N

InChi Code

InChI=1S/C15H24/c1-9-6-8-12-14(15(12,3)4)13-10(2)5-7-11(9)13/h10-14H,1,5-8H2,2-4H3/t10-,11+,12-,13-,14-/m0/s1

SMILES Code

C=C1CC[C@@]2([H])[C@@](C2(C)C)([H])[C@@]3([H])[C@@H](C)CC[C@]13[H]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMF	30.0	146.81
	DMSO	30.0	146.81
	Ethanol	30.0	146.81

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 204.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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