MedKoo Cat#: 591420 | Name: AH 3474

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AH 3474 is a biochemical.

Chemical Structure

AH 3474
AH 3474
CAS#22560-59-4

Theoretical Analysis

MedKoo Cat#: 591420

Name: AH 3474

CAS#: 22560-59-4

Chemical Formula: C13H20N2O3

Exact Mass: 252.1474

Molecular Weight: 252.31

Elemental Analysis: C, 61.88; H, 7.99; N, 11.10; O, 19.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AH 3474; AH-3474; AH3474;
IUPAC/Chemical Name
Salicylamide, 5-(2-(tert-butylamino)-1-hydroxyethyl)-
InChi Key
XJSJWMNGCFMVJB-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H20N2O3/c1-13(2,3)15-7-11(17)8-4-5-10(16)9(6-8)12(14)18/h4-6,11,15-17H,7H2,1-3H3,(H2,14,18)
SMILES Code
OC1=CC=C(C(O)CNC(C)(C)C)C=C1C(N)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Koc M, Tekin K, Tekin MI, Uzel MM, Kosekahya P, Ozulken K, Yilmazbas P. An Early Finding of Keratoconus: Increase in Corneal Densitometry. Cornea. 2018 May;37(5):580-586. doi: 10.1097/ICO.0000000000001537. PubMed PMID: 29384807. 2: Rivero-Juarez A, Lopez-Cortes LF, Castaño M, Merino D, Marquez M, Mancebo M, Cuenca-Lopez F, Jimenez-Aguilar P, Lopez-Montesinos I, Lopez-Cardenas S, Collado A, Lopez-Ruz MA, Omar M, Tellez F, Perez-Stachowski X, Hernandez-Quero J, Girón-Gonzalez JA, Fernandez-Fuertes E, Rivero A; HERACLES cohort study team of the Grupo de Estudio de Hepatitis Virales (HEPAVIR) of the Sociedad Andaluza de Enfermedades Infecciosas (SAEI). Impact of universal access to hepatitis C therapy on HIV-infected patients: implementation of the Spanish national hepatitis C strategy. Eur J Clin Microbiol Infect Dis. 2017 Mar;36(3):487-494. doi: 10.1007/s10096-016-2822-6. Epub 2016 Oct 27. PubMed PMID: 27787664; PubMed Central PMCID: PMC5309278. 3: Suzuki H, Oda I, Abe S, Sekiguchi M, Nonaka S, Yoshinaga S, Saito Y, Fukagawa T, Katai H. Clinical outcomes of early gastric cancer patients after noncurative endoscopic submucosal dissection in a large consecutive patient series. Gastric Cancer. 2017 Jul;20(4):679-689. doi: 10.1007/s10120-016-0651-z. Epub 2016 Oct 8. PubMed PMID: 27722825. 4: Zhang Y, Li F, Song Y, Sheng X, Ren F, Xiong K, Chen L, Zhang H, Liu D, Lengner CJ, Xue L, Yu Z. Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis. FASEB J. 2016 Oct;30(10):3474-3488. Epub 2016 Jul 6. PubMed PMID: 27383182. 5: Wang Q, Jin J, Maren S. Renewal of extinguished fear activates ventral hippocampal neurons projecting to the prelimbic and infralimbic cortices in rats. Neurobiol Learn Mem. 2016 Oct;134 Pt A:38-43. doi: 10.1016/j.nlm.2016.04.002. Epub 2016 Apr 7. PubMed PMID: 27060752; PubMed Central PMCID: PMC5018421. 6: Lee SG, Lee J, Kim MJ, Choi JB, Kim TH, Ban EJ, Lee CR, Kang SW, Jeong JJ, Nam KH, Jo YS, Chung WY. Long-term oncologic outcome of robotic versus open total thyroidectomy in PTC: a case-matched retrospective study. Surg Endosc. 2016 Aug;30(8):3474-9. doi: 10.1007/s00464-015-4632-9. Epub 2015 Oct 30. PubMed PMID: 26514137. 7: Beagle SD, Lockless SW. Microbiology: Electrical signalling goes bacterial. Nature. 2015 Nov 5;527(7576):44-5. doi: 10.1038/nature15641. Epub 2015 Oct 21. PubMed PMID: 26503058. 8: Li H, Wu C, Aramayo R, Sachs MS, Harlow ML. Synaptic vesicles contain small ribonucleic acids (sRNAs) including transfer RNA fragments (trfRNA) and microRNAs (miRNA). Sci Rep. 2015 Oct 8;5:14918. doi: 10.1038/srep14918. PubMed PMID: 26446566; PubMed Central PMCID: PMC4597359. 9: Vakilian H, Mirzaei M, Sharifi Tabar M, Pooyan P, Habibi Rezaee L, Parker L, Haynes PA, Gourabi H, Baharvand H, Salekdeh GH. DDX3Y, a Male-Specific Region of Y Chromosome Gene, May Modulate Neuronal Differentiation. J Proteome Res. 2015 Sep 4;14(9):3474-83. doi: 10.1021/acs.jproteome.5b00512. Epub 2015 Jul 22. PubMed PMID: 26144214. 10: Popelka H, Klionsky DJ. Post-translationally-modified structures in the autophagy machinery: an integrative perspective. FEBS J. 2015 Sep;282(18):3474-88. doi: 10.1111/febs.13356. Epub 2015 Jul 16. Review. PubMed PMID: 26108642; PubMed Central PMCID: PMC4573826. 11: Cox N, Pilling D, Gomer RH. DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):8385-90. doi: 10.1073/pnas.1500956112. Epub 2015 Jun 23. PubMed PMID: 26106150; PubMed Central PMCID: PMC4500200. 12: Gwak SJ, Koo H, Yun Y, Yhee JY, Lee HY, Yoon DH, Kim K, Ha Y. Multifunctional nanoparticles for gene delivery and spinal cord injury. J Biomed Mater Res A. 2015 Nov;103(11):3474-82. doi: 10.1002/jbm.a.35489. Epub 2015 May 19. PubMed PMID: 25904025. 13: Nice T, Pasara S, Goldfarb M, Doski J, Goldin A, Gow KW, Nuchtern JG, Vasudevan SA, Langer M, Beierle EA. Pediatric papillary thyroid cancer >1 cm: is total thyroidectomy necessary? J Pediatr Surg. 2015 Jun;50(6):1009-13. doi: 10.1016/j.jpedsurg.2015.03.031. Epub 2015 Mar 14. PubMed PMID: 25819020. 14: Tripathy SJ, Burton SD, Geramita M, Gerkin RC, Urban NN. Brain-wide analysis of electrophysiological diversity yields novel categorization of mammalian neuron types. J Neurophysiol. 2015 Jun 1;113(10):3474-89. doi: 10.1152/jn.00237.2015. Epub 2015 Mar 25. PubMed PMID: 25810482; PubMed Central PMCID: PMC4455486. 15: Goi T, Nakazawa T, Hirono Y, Yamaguchi A. The anti-tumor effect is enhanced by simultaneously targeting VEGF and PROK1 in colorectal cancer. Oncotarget. 2015 Mar 20;6(8):6053-61. PubMed PMID: 25788276; PubMed Central PMCID: PMC4467421. 16: Mittendorf EA, Ballman KV, McCall LM, Yi M, Sahin AA, Bedrosian I, Hansen N, Gabram S, Hurd T, Giuliano AE, Hunt KK. Evaluation of the stage IB designation of the American Joint Committee on Cancer staging system in breast cancer. J Clin Oncol. 2015 Apr 1;33(10):1119-27. doi: 10.1200/JCO.2014.57.2958. Epub 2014 Dec 8. PubMed PMID: 25488970; PubMed Central PMCID: PMC4372850. 17: White MJ, Galvis-Carvajal E, Gomer RH. A brief exposure to tryptase or thrombin potentiates fibrocyte differentiation in the presence of serum or serum amyloid p. J Immunol. 2015 Jan 1;194(1):142-50. doi: 10.4049/jimmunol.1401777. Epub 2014 Nov 26. PubMed PMID: 25429068; PubMed Central PMCID: PMC4272917. 18: Aiello BR, King HM, Hale ME. Functional subdivision of fin protractor and retractor muscles underlies pelvic fin walking in the African lungfish Protopterus annectens. J Exp Biol. 2014 Oct 1;217(Pt 19):3474-82. doi: 10.1242/jeb.105262. Epub 2014 Aug 7. PubMed PMID: 25104761. 19: Kong YP, Carrion B, Singh RK, Putnam AJ. Matrix identity and tractional forces influence indirect cardiac reprogramming. Sci Rep. 2013 Dec 11;3:3474. doi: 10.1038/srep03474. PubMed PMID: 24326998; PubMed Central PMCID: PMC3858798. 20: Teichmann M, Kas A, Boutet C, Ferrieux S, Nogues M, Samri D, Rogan C, Dormont D, Dubois B, Migliaccio R. Deciphering logopenic primary progressive aphasia: a clinical, imaging and biomarker investigation. Brain. 2013 Nov;136(Pt 11):3474-88. doi: 10.1093/brain/awt266. Epub 2013 Oct 8. PubMed PMID: 24108322.