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MedKoo Cat#: 596869 | Name: Argininamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Argininamide is used as a model compound in studies of the physicochemical characteristic of ligand binding DNA aptamers and their potential development as fluorescent aptasensors.

Chemical Structure

Argininamide
CAS#2788-83-2

Theoretical Analysis

MedKoo Cat#: 596869

Name: Argininamide

CAS#: 2788-83-2

Chemical Formula: C6H15N5O

Exact Mass: 173.1277

Molecular Weight: 173.22

Elemental Analysis: C, 41.60; H, 8.73; N, 40.43; O, 9.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Argininamide; L-Arginamide; L-Argininamide; L-Arginine amide;
IUPAC/Chemical Name
(S)-2-amino-5-guanidinopentanamide
InChi Key
ULEBESPCVWBNIF-BYPYZUCNSA-N
InChi Code
InChI=1S/C6H15N5O/c7-4(5(8)12)2-1-3-11-6(9)10/h4H,1-3,7H2,(H2,8,12)(H4,9,10,11)/t4-/m0/s1
SMILES Code
O=C(N)[C@@H](N)CCCNC(N)=N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 173.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Epub 2017 Feb 2. PubMed PMID: 28150423. 7: Bahamondes C, Wilson L, Bernal C, Illanes A, Álvaro G, Guzmán F. Synthesis of the kyotorphin precursor benzoyl-L-tyrosine-L-argininamide with immobilized α-chymotrypsin in sequential batch with enzyme reactivation. Biotechnol Prog. 2016 Jan-Feb;32(1):54-9. doi: 10.1002/btpr.2187. Epub 2015 Nov 6. PubMed PMID: 26488135. 8: Keller M, Weiss S, Hutzler C, Kuhn KK, Mollereau C, Dukorn S, Schindler L, Bernhardt G, König B, Buschauer A. N(ω)-Carbamoylation of the Argininamide Moiety: An Avenue to Insurmountable NPY Y1 Receptor Antagonists and a Radiolabeled Selective High-Affinity Molecular Tool ([(3)H]UR-MK299) with Extended Residence Time. J Med Chem. 2015 Nov 25;58(22):8834-49. doi: 10.1021/acs.jmedchem.5b00925. Epub 2015 Nov 4. PubMed PMID: 26466164. 9: Keller M, Schindler L, Bernhardt G, Buschauer A. Toward Labeled Argininamide-Type NPY Y1 Receptor Antagonists: Identification of a Favorable Propionylation Site in BIBO3304. 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Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: racemization studies and water-based synthesis of histidine-containing peptides. Amino Acids. 2014 Oct;46(10):2347-54. doi: 10.1007/s00726-014-1779-y. Epub 2014 Jun 26. PubMed PMID: 24965528. 14: Kraeling ME, Zhou W, Wang P, Ogunsola OA. In vitro skin penetration of acetyl hexapeptide-8 from a cosmetic formulation. Cutan Ocul Toxicol. 2015 Mar;34(1):46-52. doi: 10.3109/15569527.2014.894521. Epub 2014 Apr 22. PubMed PMID: 24754410. 15: Grosicki M, Latacz G, Szopa A, Cukier A, Kieć-Kononowicz K. The study of cellular cytotoxicity of argireline - an anti-aging peptide. Acta Biochim Pol. 2014;61(1):29-32. Epub 2014 Mar 17. PubMed PMID: 24644551. 16: Zhao Q, Zhang Z, Xu L, Xia T, Li N, Liu J, Fang X. Exonuclease I aided enzyme-linked aptamer assay for small-molecule detection. Anal Bioanal Chem. 2014 May;406(12):2949-55. doi: 10.1007/s00216-014-7705-z. Epub 2014 Mar 6. PubMed PMID: 24599422. 17: Sadatmousavi P, Chen P. Self/co-assembling peptide, EAR8-II, as a potential carrier for a hydrophobic anticancer drug pirarubicin (THP)--characterization and in-vitro delivery. Int J Mol Sci. 2013 Nov 26;14(12):23315-29. doi: 10.3390/ijms141223315. PubMed PMID: 24287908; PubMed Central PMCID: PMC3876047. 18: Severino B, Incisivo GM, Fiorino F, Bertolino A, Frecentese F, Barbato F, Manganelli S, Maggioni G, Capasso D, Caliendo G, Santagada V, Sorrentino R, Roviezzo F, Perissutti E. Identification of a pepducin acting as S1P3 receptor antagonist. J Pept Sci. 2013 Nov;19(11):717-24. doi: 10.1002/psc.2554. Epub 2013 Sep 20. PubMed PMID: 24133031. 19: Keller M, Kaske M, Holzammer T, Bernhardt G, Buschauer A. Dimeric argininamide-type neuropeptide Y receptor antagonists: chiral discrimination between Y1 and Y4 receptors. Bioorg Med Chem. 2013 Nov 1;21(21):6303-22. doi: 10.1016/j.bmc.2013.08.065. Epub 2013 Sep 8. 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