MedKoo Cat#: 596814 | Name: Peptide pva

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Peptide pva is Encoded by an RNA that is complementary to arginine vasopressin mRNA.

Chemical Structure

Peptide pva
Peptide pva
CAS#114472-81-0

Theoretical Analysis

MedKoo Cat#: 596814

Name: Peptide pva

CAS#: 114472-81-0

Chemical Formula: C44H68N10O14

Exact Mass: 960.4916

Molecular Weight: 961.08

Elemental Analysis: C, 54.99; H, 7.13; N, 14.57; O, 23.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Peptide pva; Vasopressin antisense peptide;
IUPAC/Chemical Name
(2S,5S,8S,11S,14S,17S,20S,23S,26S)-20-((1H-indol-3-yl)methyl)-26-amino-8-(2-carboxyethyl)-27-hydroxy-23-(hydroxymethyl)-11-isobutyl-5,14-diisopropyl-2,17-dimethyl-4,7,10,13,16,19,22,25-octaoxo-3,6,9,12,15,18,21,24-octaazaheptacosanoic acid
InChi Key
CSSCNAQAPMBKBR-UIXLVMMTSA-N
InChi Code
InChI=1S/C44H68N10O14/c1-20(2)15-30(40(63)49-29(13-14-33(57)58)38(61)54-34(21(3)4)42(65)48-24(8)44(67)68)51-43(66)35(22(5)6)53-36(59)23(7)47-39(62)31(16-25-17-46-28-12-10-9-11-26(25)28)50-41(64)32(19-56)52-37(60)27(45)18-55/h9-12,17,20-24,27,29-32,34-35,46,55-56H,13-16,18-19,45H2,1-8H3,(H,47,62)(H,48,65)(H,49,63)(H,50,64)(H,51,66)(H,52,60)(H,53,59)(H,54,61)(H,57,58)(H,67,68)/t23-,24-,27-,29-,30-,31-,32-,34-,35-/m0/s1
SMILES Code
C[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](C(C)C)NC([C@H](C)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CO)NC([C@H](CO)N)=O)=O)=O)=O)=O)=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 961.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bélanger D, Tong X, Soumaré S, Dory YL, Zhao Y. Cyclic peptide-polymer complexes and their self-assembly. Chemistry. 2009;15(17):4428-36. doi: 10.1002/chem.200802337. PubMed PMID: 19263443. 2: Fainerman VB, Lucassen-Reynders EH, Miller R. Description of the adsorption behaviour of proteins at water/fluid interfaces in the framework of a two-dimensional solution model. Adv Colloid Interface Sci. 2003 Dec 1;106:237-59. PubMed PMID: 14672849. 3: Jurzak M, Pavo I, Fahrenholz F. Lack of interaction of vasopressin with its antisense peptides: a functional and immunological study. J Recept Res. 1993;13(5):881-902. PubMed PMID: 8385219. 4: Kelly JM, Trinder D, Phillips PA, Casley DJ, Kemp B, Mooser V, Johnston CI. Vasopressin antisense peptide interactions with the V1 receptor. Peptides. 1990 Jul-Aug;11(4):857-62. PubMed PMID: 2146598. 5: Swords BH, Carr DJ, Blalock JE, Berecek KH. An antibody directed against a peptide encoded by RNA complementary to mRNA for vasopressin recognizes putative vasopressin receptors. Neuroendocrinology. 1990 Apr;51(4):487-92. PubMed PMID: 2140594. 6: Knigge KM, Piekut DT, Berlove D. Immunocytochemistry of a vasopressin (AVP) receptor with anti-idiotype antibody: inhibition of staining with a peptide (PVA) encoded by an RNA that is complementary to AVP mRNA. Neurosci Lett. 1988 Apr 12;86(3):269-71. PubMed PMID: 3380318.