Insulin B (22-30) | CAS#89270-99-5 | peptide hormone

MedKoo Cat#: 596809 | Name: Insulin B (22-30)

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Insulin B (22-30) is a peptide hormone produced by beta cells of the pancreatic islets, and it is considered to be the main anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially glucose from the blood into liver, fat and skeletal muscle cells. In these tissues the absorbed glucose is converted into either glycogen via glycogenesis or fats (triglycerides) via lipogenesis, or, in the case of the liver, into both. Glucose production and secretion by the liver is strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is therefore an anabolic hormone, promoting the conversion of small molecules in the blood into large molecules inside the cells. Low insulin levels in the blood have the opposite effect by promoting widespread catabolism, especially of reserve body fat.

Chemical Structure

Insulin B (22-30)

CAS#89270-99-5

Theoretical Analysis

MedKoo Cat#: 596809

Name: Insulin B (22-30)

CAS#: 89270-99-5

Chemical Formula: C53H75N13O12

Exact Mass: 1085.5658

Molecular Weight: 1086.26

Elemental Analysis: C, 58.60; H, 6.96; N, 16.76; O, 17.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Insulin B (22-30); Insulin (B22-B30);

IUPAC/Chemical Name

L-arginylglycyl-L-phenylalanyl-L-phenylalanyl-L-tyrosyl-L-threonyl-L-prolyl-L-lysyl-L-alanine

InChi Key

YFZCWRCBISUCFG-ZDMORDKWSA-N

InChi Code

InChI=1S/C53H75N13O12/c1-31(52(77)78)60-46(71)38(18-9-10-24-54)62-50(75)42-19-12-26-66(42)51(76)44(32(2)67)65-49(74)41(29-35-20-22-36(68)23-21-35)64-48(73)40(28-34-15-7-4-8-16-34)63-47(72)39(27-33-13-5-3-6-14-33)61-43(69)30-59-45(70)37(55)17-11-25-58-53(56)57/h3-8,13-16,20-23,31-32,37-42,44,67-68H,9-12,17-19,24-30,54-55H2,1-2H3,(H,59,70)(H,60,71)(H,61,69)(H,62,75)(H,63,72)(H,64,73)(H,65,74)(H,77,78)(H4,56,57,58)/t31-,32+,37-,38-,39-,40-,41-,42-,44-/m0/s1

SMILES Code

C[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H]1N(C([C@H]([C@H](O)C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC4=CC=CC=C4)NC(CNC([C@H](CCCNC(N)=N)N)=O)=O)=O)=O)=O)=O)CCC1)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,086.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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