MedKoo Cat#: 596805 | Name: Eisenin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Eisenin is isolated from brown marine algae, Eisenia bicyclis Setchell; shows activity as a biological response modifier.

Chemical Structure

Eisenin
Eisenin
CAS#21477-57-6

Theoretical Analysis

MedKoo Cat#: 596805

Name: Eisenin

CAS#: 21477-57-6

Chemical Formula: C13H20N4O6

Exact Mass: 328.1383

Molecular Weight: 328.32

Elemental Analysis: C, 47.56; H, 6.14; N, 17.06; O, 29.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Eisenin; Pglu-gln-ala; Pyroglutamyl-glutaminyl-alanine;
IUPAC/Chemical Name
((S)-5-oxopyrrolidine-2-carbonyl)-L-glutaminyl-L-alanine
InChi Key
VIPNGHPLCAMVEB-FXQIFTODSA-N
InChi Code
InChI=1S/C13H20N4O6/c1-6(13(22)23)15-11(20)8(2-4-9(14)18)17-12(21)7-3-5-10(19)16-7/h6-8H,2-5H2,1H3,(H2,14,18)(H,15,20)(H,16,19)(H,17,21)(H,22,23)/t6-,7-,8-/m0/s1
SMILES Code
C[C@@H](C(O)=O)NC([C@H](CCC(N)=O)NC([C@H](CC1)NC1=O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 328.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Genotoxic Assessment of Different Sizes of Iron Oxide Nanoparticles and Ionic Iron in Earthworm (Eisenia hortensis) Coelomocytes by Comet Assay and Micronucleus Test. Bull Environ Contam Toxicol. 2018 May 25. doi: 10.1007/s00128-018-2364-y. [Epub ahead of print] PubMed PMID: 29802429. 5: Liu Z, Xiong Y, Yi L, Dai R, Wang Y, Sun M, Shao X, Zhang Z, Yuan S. Endo-β-1,3-glucanase digestion combined with the HPAEC-PAD-MS/MS analysis reveals the structural differences between two laminarins with different bioactivities. Carbohydr Polym. 2018 Aug 15;194:339-349. doi: 10.1016/j.carbpol.2018.04.044. Epub 2018 Apr 14. PubMed PMID: 29801847. 6: Wang X, Li X, Sun Z. iTRAQ-based quantitative proteomic analysis of the earthworm Eisenia fetida response to Escherichia coli O157:H7. Ecotoxicol Environ Saf. 2018 Sep 30;160:60-66. doi: 10.1016/j.ecoenv.2018.05.007. Epub 2018 May 21. PubMed PMID: 29793202. 7: Zhao S, Wang B, Zhu L, Liang T, Chen M, Yang L, Lv J, Liu L. Uptake, elimination and biotransformation of N-ethyl perfluorooctane sulfonamide (N-EtFOSA) by the earthworms (Eisenia fetida) after in vivo and in vitro exposure. Environ Pollut. 2018 May 21;241:19-25. doi: 10.1016/j.envpol.2018.05.046. [Epub ahead of print] PubMed PMID: 29793104. 8: Roubalová R, Dvořák J, Procházková P, Škanta F, Navarro Pacheco Natividad I, Semerád J, Cajthaml T, Bilej M. The role of CuZn- and Mn-superoxide dismutases in earthworm Eisenia andrei kept in two distinct field-contaminated soils. Ecotoxicol Environ Saf. 2018 Sep 15;159:363-371. doi: 10.1016/j.ecoenv.2018.04.056. Epub 2018 May 21. PubMed PMID: 29778984. 9: Liang R, Chen J, Shi Y, Lu Y, Sarvajayakesavalu S, Xu X, Zheng X, Khan K, Su C. Toxicological effects on earthworms (Eisenia fetida) exposed to sub-lethal concentrations of BDE-47 and BDE-209 from a metabolic point. Environ Pollut. 2018 May 15;240:653-660. doi: 10.1016/j.envpol.2018.04.145. [Epub ahead of print] PubMed PMID: 29775942. 10: Majumdar A, Barla A, Upadhyay MK, Ghosh D, Chaudhuri P, Srivastava S, Bose S. Vermiremediation of metal(loid)s via Eichornia crassipes phytomass extraction: A sustainable technique for plant amelioration. J Environ Manage. 2018 Aug 15;220:118-125. doi: 10.1016/j.jenvman.2018.05.017. Epub 2018 May 26. PubMed PMID: 29775821. 11: Shao Y, Wang J, Du Z, Li B, Zhu L, Wang J. Toxicity of 1-alkyl-3-methyl imidazolium nitrate ionic liquids to earthworms: The effects of carbon chains of different lengths. Chemosphere. 2018 May 4;206:302-309. doi: 10.1016/j.chemosphere.2018.04.114. [Epub ahead of print] PubMed PMID: 29754054. 12: Saha T, Chakraborty B, Das S, Thakur N, Chakraborty R. Chryseomicrobium excrementi sp. nov., a Gram-stain-positive rod-shaped bacterium isolated from an earthworm (Eisenia fetida) cast. Int J Syst Evol Microbiol. 2018 May 11. doi: 10.1099/ijsem.0.002791. [Epub ahead of print] PubMed PMID: 29749923. 13: Zhu W, Yao W, Shen X, Zhang W, Xu H. Heavy metal and δ(13)C value variations and characterization of dissolved organic matter (DOM) during vermicomposting of pig manure amended with (13)C-labeled rice straw. Environ Sci Pollut Res Int. 2018 May 10. doi: 10.1007/s11356-018-2016-0. [Epub ahead of print] PubMed PMID: 29748804. 14: Yang G, Li J, Wang Y, Chen C, Zhao H, Shao K. Quantitative ecotoxicity analysis for pesticide mixtures using benchmark dose methodology. Ecotoxicol Environ Saf. 2018 Sep 15;159:94-101. doi: 10.1016/j.ecoenv.2018.04.055. Epub 2018 May 3. PubMed PMID: 29730414. 15: Mariyadas J, Amorim MJB, Jensen J, Scott-Fordsmand JJ. Earthworm avoidance of silver nanomaterials over time. Environ Pollut. 2018 Aug;239:751-756. doi: 10.1016/j.envpol.2018.04.059. Epub 2018 May 2. PubMed PMID: 29729616. 16: Gainer A, Cousins M, Hogan N, Siciliano SD. Petroleum Hydrocarbon Mixture Toxicity and a Trait Based Approach to Soil Invertebrate Species for Site Specific Risk Assessments. Environ Toxicol Chem. 2018 May 5. doi: 10.1002/etc.4164. [Epub ahead of print] PubMed PMID: 29729033. 17: Zaltauskaite J, Miskelyte D. Biochemical and life cycle effects of triclosan chronic toxicity to earthworm Eisenia fetida. Environ Sci Pollut Res Int. 2018 May 2. doi: 10.1007/s11356-018-2065-4. [Epub ahead of print] PubMed PMID: 29717430. 18: Coelho C, Foret C, Bazin C, Leduc L, Hammada M, Inácio M, Bedell JP. Bioavailability and bioaccumulation of heavy metals of several soils and sediments (from industrialized urban areas) for Eisenia fetida. Sci Total Environ. 2018 Sep 1;635:1317-1330. doi: 10.1016/j.scitotenv.2018.04.213. Epub 2018 Apr 24. PubMed PMID: 29710585. 19: Masin CE, Lescano MR, Rodríguez AR, Godoy JL, Zalazar CS. Earthworms to assess the innocuousness of spent biomixtures employed for glyphosate degradation. 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