MedKoo Cat#: 591373 | Name: Racemic rasagiline

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Racemic rasagiline, also known as AGN-1135, is a monoamine oxidase type-B inhibitor (MAOI) that is not metabolized to amphetamine derivatives. However, application of this drug can lead to fatal hypertensive crisis in patients who consume tyramine-rich foods. TVP-1022 is the (S)-isomer os Rasagiline and acts as a cardioprotective agent.

Chemical Structure

Racemic rasagiline
Racemic rasagiline
CAS#1875-50-9

Theoretical Analysis

MedKoo Cat#: 591373

Name: Racemic rasagiline

CAS#: 1875-50-9

Chemical Formula: C12H13N

Exact Mass: 171.1048

Molecular Weight: 171.24

Elemental Analysis: C, 84.17; H, 7.65; N, 8.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Racemic rasagiline; Agn-1135; Agn 1135; Agn1135;
IUPAC/Chemical Name
1H-Inden-1-amine, 2,3-dihydro-N-2-propynyl-
InChi Key
RUOKEQAAGRXIBM-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2
SMILES Code
C#CCNC1CCC2=C1C=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 171.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tak KM, Park EJ, Hyun MH. Liquid chromatographic resolution of racemic rasagiline and its analogues on a chiral stationary phase based on (+)-(18-crown-6)-2,3,11,12-tetracarboxylic acid. J Sep Sci. 2013 Dec;36(23):3682-7. doi: 10.1002/jssc.201300819. Epub 2013 Oct 9. PubMed PMID: 24106082. 2: Youdim MB, Gross A, Finberg JP. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132(2):500-6. PubMed PMID: 11159700; PubMed Central PMCID: PMC1572573. 3: Speiser Z, Levy R, Cohen S. Effects of N-propargyl-1-(R)aminoindan (rasagiline) in models of motor and cognition disorders. J Neural Transm Suppl. 1998;52:287-300. PubMed PMID: 9564629.