CAP-53194 | CAS#660817-08-3 | Plk1 inhibitor

MedKoo Cat#: 562935 | Name: CAP-53194

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CAP-53194 is a potent and selective Plk1 inhibitor.

Chemical Structure

CAP-53194

CAS#660817-08-3

Theoretical Analysis

MedKoo Cat#: 562935

Name: CAP-53194

CAS#: 660817-08-3

Chemical Formula: C21H14N6O5

Exact Mass: 430.1026

Molecular Weight: 430.38

Elemental Analysis: C, 58.61; H, 3.28; N, 19.53; O, 18.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

CAP-53194; CAP 53194; CAP53194;

IUPAC/Chemical Name

N,1-Bis(4-nitrophenyl)-5-phenyl-1H-1,2,3-Triazole-4-carboxamide

InChi Key

ORYIDPDQYDBZQA-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H14N6O5/c28-21(22-15-6-8-17(9-7-15)26(29)30)19-20(14-4-2-1-3-5-14)25(24-23-19)16-10-12-18(13-11-16)27(31)32/h1-13H,(H,22,28)

SMILES Code

O=C(C1=C(C2=CC=CC=C2)N(C3=CC=C([N+]([O-])=O)C=C3)N=N1)NC4=CC=C([N+]([O-])=O)C=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 430.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Shino N, Uchida T, Yoshida M, Nomura Y. Development and Assessment of a Nomogram to Propose the Initial Dosage Regimen of a Meropenem Infusion Based on Serum Creatinine and Age Using a Monte Carlo Simulation. Chem Pharm Bull (Tokyo). 2015;63(12):986-91. doi: 10.1248/cpb.c15-00494. PubMed PMID: 26633021. 2: Wang L, Kim M, Fang Q, Min J, Jeon WI, Lee SY, Son SJ, Joo SW, Lee SB. Hydrophobic end-gated silica nanotubes for intracellular glutathione-stimulated drug delivery in drug-resistant cancer cells. Chem Commun (Camb). 2013 Apr 21;49(31):3194-6. doi: 10.1039/c3cc38761e. Epub 2013 Feb 15. PubMed PMID: 23417143.