TachypleginA | CAS#331839-29-3 | parasite inhibitor

MedKoo Cat#: 562928 | Name: TachypleginA

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TachypleginA is an Inhibitor of parasite motility and invasion.

Chemical Structure

TachypleginA

CAS#331839-29-3

Theoretical Analysis

MedKoo Cat#: 562928

Name: TachypleginA

CAS#: 331839-29-3

Chemical Formula: C22H21F2NO

Exact Mass: 353.1591

Molecular Weight: 353.41

Elemental Analysis: C, 74.77; H, 5.99; F, 10.75; N, 3.96; O, 4.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

TachypleginA; Tachyplegin A; Tachyplegin-A;

IUPAC/Chemical Name

3,5-bis((E)-4-fluorobenzylidene)-1-propylpiperidin-4-one

InChi Key

VIFODPVYCOAIJX-KLCVKJMQSA-N

InChi Code

InChI=1S/C22H21F2NO/c1-2-11-25-14-18(12-16-3-7-20(23)8-4-16)22(26)19(15-25)13-17-5-9-21(24)10-6-17/h3-10,12-13H,2,11,14-15H2,1H3/b18-12+,19-13+

SMILES Code

FC1=CC=C(/C=C2CN(CCC)C/C(C\2=O)=C\C3=CC=C(F)C=C3)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 353.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Leung JM, Tran F, Pathak RB, Poupart S, Heaslip AT, Ballif BA, Westwood NJ, Ward GE. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. PLoS One. 2014 Jun 3;9(6):e98056. doi: 10.1371/journal.pone.0098056. eCollection 2014. PubMed PMID: 24892871; PubMed Central PMCID: PMC4043638.