Synonym
BIMU-1; BIMU 1; BIMU1;
IUPAC/Chemical Name
3-ethyl-N-((1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-6-yl)-2,3-dihydro-1H-benzo[d]imidazole-1-carboxamide
InChi Key
ZMVTYVHIVVTKJO-LOWNFYCTSA-N
InChi Code
InChI=1S/C18H26N4O/c1-3-21-12-22(17-9-5-4-8-16(17)21)18(23)19-14-11-13-7-6-10-15(14)20(13)2/h4-5,8-9,13-15H,3,6-7,10-12H2,1-2H3,(H,19,23)/t13-,14?,15+/m1/s1
SMILES Code
CCN1C2=CC=CC=C2N(C(NC3[C@@H](N4C)CCC[C@@H]4C3)=O)C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
314.43
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1. Ramakrishna Nirogi, Abdul Rasheed Mohammed, Anil K. Shinde, Shankar Reddy Gagginapally, Durga Malleshwari Kancharla, Vanaja Reddy Middekadi, Narsimha Bogaraju, Srinivasa Rao Ravella, Pooja Singh, Sumit Raosaheb Birangal, Ramkumar Subramanian, Raghava Choudary Palacharla, Vijay Benade, Nageswararao Muddana, and Pradeep Jayarajan. Synthesis, Structure–Activity Relationships, and Preclinical Evaluation of Heteroaromatic Amides and 1,3,4-Oxadiazole Derivatives as 5-HT4 Receptor Partial Agonists. Publication Date (Web): May 15, 2018 (Article)
DOI: 10.1021/acs.jmedchem.8b00457
