L 668411 | 112965-15-8 | HMG-CoA synthase inhibitor

MedKoo Cat#: 596614 | Name: L 668411

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 668411 is the 2,3-ditritiated methyl ester of L 659699; inhibits HMG-CoA synthase.

Chemical Structure

L 668411

CAS#112965-15-8

Theoretical Analysis

MedKoo Cat#: 596614

Name: L 668411

CAS#: 112965-15-8

Chemical Formula: C19H30O5

Exact Mass: 338.2093

Molecular Weight: 338.44

Elemental Analysis: C, 67.43; H, 8.94; O, 23.64

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

L 668411; L 668411; L 668411; L-668,411; L 668,411; L668,411;

IUPAC/Chemical Name

methyl (2E,4E)-11-((2S,3S)-3-(hydroxymethyl)-4-oxooxetan-2-yl)-3,5,7-trimethylundeca-2,4-dienoate

InChi Key

MMICHQCZQPCQGB-AOCVOAOWSA-N

InChi Code

InChI=1S/C19H30O5/c1-13(9-14(2)10-15(3)11-18(21)23-4)7-5-6-8-17-16(12-20)19(22)24-17/h10-11,13,16-17,20H,5-9,12H2,1-4H3/b14-10+,15-11+/t13?,16-,17-/m0/s1

SMILES Code

O=C(OC)/C=C(C)/C=C(C)/CC(C)CCCC[C@@H]([C@@H]1CO)OC1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Greenspan MD, Bull HG, Yudkovitz JB, Hanf DP, Alberts AW. Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase and cholesterol biosynthesis by beta-lactone inhibitors and binding of these inhibitors to the enzyme. Biochem J. 1993 Feb 1;289 ( Pt 3):889-95. PubMed PMID: 8094614; PubMed Central PMCID: PMC1132259.