MedKoo Cat#: 596596 | Name: L 653150

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 653150 is a platelet activating factor antagaonist.

Chemical Structure

L 653150
L 653150
CAS#101394-50-7

Theoretical Analysis

MedKoo Cat#: 596596

Name: L 653150

CAS#: 101394-50-7

Chemical Formula: C22H28O6S

Exact Mass: 420.1607

Molecular Weight: 420.52

Elemental Analysis: C, 62.84; H, 6.71; O, 22.83; S, 7.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
L 653150; L-653150; L653150;
IUPAC/Chemical Name
(2R,5R)-2,5-bis(3,4,5-trimethoxyphenyl)tetrahydrothiophene
InChi Key
LRKDYEMHDRMUKA-WOJBJXKFSA-N
InChi Code
InChI=1S/C22H28O6S/c1-23-15-9-13(10-16(24-2)21(15)27-5)19-7-8-20(29-19)14-11-17(25-3)22(28-6)18(12-14)26-4/h9-12,19-20H,7-8H2,1-6H3/t19-,20-/m1/s1
SMILES Code
COC1=C(OC)C(OC)=CC([C@H]2CC[C@H](C3=CC(OC)=C(OC)C(OC)=C3)S2)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 420.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang J, Dunn MJ. Platelet-activating factor mediates endotoxin-induced acute renal insufficiency in rats. Am J Physiol. 1987 Dec;253(6 Pt 2):F1283-9. PubMed PMID: 2827506. 2: Patrignani P, Valitutti S, Aiello F, Musiani P. Platelet-activating factor (PAF) receptor antagonists inhibit mitogen-induced human peripheral blood T-cell proliferation. Biochem Biophys Res Commun. 1987 Oct 29;148(2):802-10. PubMed PMID: 2825672. 3: Hwang SB, Lam MH. Species difference in the specific receptors of platelet activating factor. Biochem Pharmacol. 1986 Dec 15;35(24):4511-8. PubMed PMID: 3024653.