MedKoo Cat#: 562906 | Name: Carazostatin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Carazostatin is an antioxidant, free radical scavenger and potent inhibitor of lipid peroxidation.

Chemical Structure

Carazostatin
Carazostatin
CAS#126168-32-9

Theoretical Analysis

MedKoo Cat#: 562906

Name: Carazostatin

CAS#: 126168-32-9

Chemical Formula: C20H25NO

Exact Mass: 295.1936

Molecular Weight: 295.42

Elemental Analysis: C, 81.31; H, 8.53; N, 4.74; O, 5.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Carazostatin;
IUPAC/Chemical Name
1-Heptyl-2-methyl-9H-carbazol-3-ol
InChi Key
ADLBIVFEKWBVKQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H25NO/c1-3-4-5-6-7-10-15-14(2)19(22)13-17-16-11-8-9-12-18(16)21-20(15)17/h8-9,11-13,21-22H,3-7,10H2,1-2H3
SMILES Code
OC1=CC2=C(C(CCCCCCC)=C1C)NC3=C2C=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 295.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hieda Y, Anraku M, Choshi T, Tomida H, Fujioka H, Hatae N, Hori O, Hirose J, Hibino S. Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3530-3. doi: 10.1016/j.bmcl.2014.05.050. Epub 2014 May 27. PubMed PMID: 24928405. 2: Sakamoto M, Kawasaki T, Ishii K, Tamura O. [The chemistry of pericyclic reactions and their application to syntheses of heterocyclic compounds]. Yakugaku Zasshi. 2003 Sep;123(9):717-59. Review. Japanese. PubMed PMID: 14513766. 3: Choshi T, Sada T, Fujimoto H, Nagayama C, Sugino E, Hibino S. Total Syntheses of Carazostatin, Hyellazole, and Carbazoquinocins B-F. J Org Chem. 1997 Apr 18;62(8):2535-2543. PubMed PMID: 11671594. 4: Kato S, Kawasaki T, Urata T, Mochizuki J. In vitro and ex vivo free radical scavenging activities of carazostatin, carbazomycin B and their derivatives. J Antibiot (Tokyo). 1993 Dec;46(12):1859-65. PubMed PMID: 8294245. 5: Iwatsuki M, Niki E, Kato S. Antioxidant activities of natural and synthetic carbazoles. Biofactors. 1993 May;4(2):123-8. PubMed PMID: 8394091. 6: Kato S, Kawai H, Kawasaki T, Toda Y, Urata T, Hayakawa Y. Studies on free radical scavenging substances from microorganisms. I. Carazostatin, a new free radical scavenger produced by Streptomyces chromofuscus DC 118. J Antibiot (Tokyo). 1989 Dec;42(12):1879-81. PubMed PMID: 2621170.