IUPAC/Chemical Name
1-Heptyl-2-methyl-9H-carbazol-3-ol
InChi Key
ADLBIVFEKWBVKQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H25NO/c1-3-4-5-6-7-10-15-14(2)19(22)13-17-16-11-8-9-12-18(16)21-20(15)17/h8-9,11-13,21-22H,3-7,10H2,1-2H3
SMILES Code
OC1=CC2=C(C(CCCCCCC)=C1C)NC3=C2C=CC=C3
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
295.42
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Hieda Y, Anraku M, Choshi T, Tomida H, Fujioka H, Hatae N, Hori O, Hirose J, Hibino S. Antioxidant effects of the highly-substituted carbazole alkaloids and their related carbazoles. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3530-3. doi: 10.1016/j.bmcl.2014.05.050. Epub 2014 May 27. PubMed PMID: 24928405.
2: Sakamoto M, Kawasaki T, Ishii K, Tamura O. [The chemistry of pericyclic reactions and their application to syntheses of heterocyclic compounds]. Yakugaku Zasshi. 2003 Sep;123(9):717-59. Review. Japanese. PubMed PMID: 14513766.
3: Choshi T, Sada T, Fujimoto H, Nagayama C, Sugino E, Hibino S. Total Syntheses of Carazostatin, Hyellazole, and Carbazoquinocins B-F. J Org Chem. 1997 Apr 18;62(8):2535-2543. PubMed PMID: 11671594.
4: Kato S, Kawasaki T, Urata T, Mochizuki J. In vitro and ex vivo free radical scavenging activities of carazostatin, carbazomycin B and their derivatives. J Antibiot (Tokyo). 1993 Dec;46(12):1859-65. PubMed PMID: 8294245.
5: Iwatsuki M, Niki E, Kato S. Antioxidant activities of natural and synthetic carbazoles. Biofactors. 1993 May;4(2):123-8. PubMed PMID: 8394091.
6: Kato S, Kawai H, Kawasaki T, Toda Y, Urata T, Hayakawa Y. Studies on free radical scavenging substances from microorganisms. I. Carazostatin, a new free radical scavenger produced by Streptomyces chromofuscus DC 118. J Antibiot (Tokyo). 1989 Dec;42(12):1879-81. PubMed PMID: 2621170.