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MedKoo Cat#: 596584 | Name: L 646462

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 646462 is an antidopaminergic agent.

Chemical Structure

L 646462
L 646462
CAS#89149-85-9

Theoretical Analysis

MedKoo Cat#: 596584

Name: L 646462

CAS#: 89149-85-9

Chemical Formula: C27H27N3O4

Exact Mass: 457.2002

Molecular Weight: 457.53

Elemental Analysis: C, 70.88; H, 5.95; N, 9.18; O, 13.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
L 646462; L-646462; L646462; L-646,462; L 646,462; L646,462;
IUPAC/Chemical Name
(3-methyl-2,5-dioxoimidazolidin-1-yl)methyl 5-(1-methylpiperidin-4-ylidene)-5H-dibenzo[a,d][7]annulene-3-carboxylate
InChi Key
LEHDAQHCDVGZCX-UHFFFAOYSA-N
InChi Code
InChI=1S/C27H27N3O4/c1-28-13-11-20(12-14-28)25-22-6-4-3-5-18(22)7-8-19-9-10-21(15-23(19)25)26(32)34-17-30-24(31)16-29(2)27(30)33/h3-10,15H,11-14,16-17H2,1-2H3
SMILES Code
CN(CC/1)CCC1=C2c3cc(C(OCN4C(CN(C)C4=O)=O)=O)ccc3C=Cc5ccccc/25
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 457.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Williams M, Martin GE, Remy DC, Hichens M, Mangel AW, Taylor DA, Yarbrough GG, Bendesky RJ, King SW, Robinson JL, et al. L-646,462, a cyproheptadine-related antagonist of dopamine and serotonin with selectivity for peripheral systems. J Pharmacol Exp Ther. 1984 Jun;229(3):775-81. PubMed PMID: 6547178.