Synonym
Mecarbam; MS 1053; MS 1143
IUPAC/Chemical Name
7-Oxa-5-thia-2-aza-6-phosphanonanoic acid, 6-ethoxy-2-methyl-3-oxo-, ethyl ester, 6-sulfide
InChi Key
KLGMSAOQDHLCOS-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H20NO5PS2/c1-5-14-10(13)11(4)9(12)8-19-17(18,15-6-2)16-7-3/h5-8H2,1-4H3
SMILES Code
CCOP(SCC(N(C)C(OCC)=O)=O)(OCC)=S
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Biological target:
Mecarbam is a pesticide.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
329.37
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
Formulation protocol:
TBD
1: Góralczyk K, Struciński P, Hernik A, Czaja K, Korcz W, Ludwicki JK. [Monitoring and official control of pesticide residues in foodstuffs in Poland in 2004]. Rocz Panstw Zakl Hig. 2005;56(4):307-16. Polish. PubMed PMID: 16610666.
2: Tsatsakis AM, Aguridakis P, Michalodimitrakis MN, Tsakalov AK, Alegakis AK, Koumantakis E, Troulakis G. Experiences with acute organophosphate poisonings in Crete. Vet Hum Toxicol. 1996 Apr;38(2):101-7. PubMed PMID: 8693683.
3: Senanayake N. Neuropathy following acute intoxication with Mecarbam (OP ester). Acta Neurol Scand. 1992 Jan;85(1):77. PubMed PMID: 1546539.
4: Stamboulis E, Psimaras A, Vassilopoulos D, Davaki P, Manta P, Kapaki E. Neuropathy following acute intoxication with Mecarbam (OP ester). Acta Neurol Scand. 1991 Mar;83(3):198-200. PubMed PMID: 1851595.
5: Tsoukali-Papadopoulou H, Njau S. Mother-fetus postmortem toxicologic analysis in a fatal overdose with mecarbam. Forensic Sci Int. 1987 Dec;35(4):249-52. PubMed PMID: 3428806.
6: Greenberg RS. Gas chromatographic determination of mecarbam and its metabolites mecarboxon, diethoate, and diethoxon in cottonseeds. J Assoc Off Anal Chem. 1987 Sep-Oct;70(5):870-4. PubMed PMID: 2824431.
