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MedKoo Cat#: 596570 | Name: L-6355

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L-6355 is a bioactive chemical.

Chemical Structure

L-6355
L-6355
CAS#85642-08-6

Theoretical Analysis

MedKoo Cat#: 596570

Name: L-6355

CAS#: 85642-08-6

Chemical Formula: C25H30INO3

Exact Mass: 519.1270

Molecular Weight: 519.42

Elemental Analysis: C, 57.81; H, 5.82; I, 24.43; N, 2.70; O, 9.24

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Related CAS #
No Data
Synonym
L-6355; L 6355; L6355; Demonoiodoamiodarone; Amiodarone related compound E; Amiodarone hydrochloride impurity C [EP];
IUPAC/Chemical Name
(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3-iodophenyl)methanone
InChi Key
DKWLFFXBYKTKRM-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H30INO3/c1-4-7-11-23-24(19-10-8-9-12-21(19)30-23)25(28)18-13-14-22(20(26)17-18)29-16-15-27(5-2)6-3/h8-10,12-14,17H,4-7,11,15-16H2,1-3H3
SMILES Code
O=C(C1=C(CCCC)OC2=CC=CC=C12)C3=CC=C(OCCN(CC)CC)C(I)=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
L-6355 is a bioactive chemical.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 519.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Sase A, Nawaratna G, Hu S, Wu G, Lubec G. Decreased hippocampal homoarginine and increased nitric oxide and nitric oxide synthase levels in rats parallel training in a radial arm maze. Amino Acids. 2016 Sep;48(9):2197-204. doi: 10.1007/s00726-016-2251-y. Epub 2016 May 13. PubMed PMID: 27178025. 2: Bernardes PC, de Andrade NJ, da Silva LH, de Carvalho AF, Fernandes PÉ, Araújo EA, Lelis CA, Mol PC, de Sá JP. Modification of polysulfone membrane used in the water filtration process to reduce biofouling. J Nanosci Nanotechnol. 2014 Aug;14(8):6355-67. PubMed PMID: 25936118. 3: Venzo A, Antonello S, Gascón JA, Guryanov I, Leapman RD, Perera NV, Sousa A, Zamuner M, Zanella A, Maran F. Effect of the charge state (z = -1, 0, +1) on the nuclear magnetic resonance of monodisperse Au25[S(CH2)2Ph]18(z) clusters. Anal Chem. 2011 Aug 15;83(16):6355-62. doi: 10.1021/ac2012653. Epub 2011 Jul 27. PubMed PMID: 21718063. 4: Shen L, Suresh L, Wu J, Xuan J, Li H, Zhang C, Pankewycz O, Ambrus JL Jr. A role for lymphotoxin in primary Sjogren's disease. J Immunol. 2010 Nov 15;185(10):6355-63. doi: 10.4049/jimmunol.1001520. Epub 2010 Oct 15. PubMed PMID: 20952683. 5: Lonardoni MV, Russo M, Jancar S. Essential role of platelet-activating factor in control of Leishmania (Leishmania) amazonensis infection. Infect Immun. 2000 Nov;68(11):6355-61. PubMed PMID: 11035745; PubMed Central PMCID: PMC97719. 6: Hermann PM, van Kesteren RE, Wildering WC, Painter SD, Reno JM, Smith JS, Kumar SB, Geraerts WP, Ericsson LH, Smit AB, Bulloch AG, Nagle GT. Neurotrophic actions of a novel molluscan epidermal growth factor. J Neurosci. 2000 Sep 1;20(17):6355-64. PubMed PMID: 10964941. 7: Zhou A, Paranjape J, Brown TL, Nie H, Naik S, Dong B, Chang A, Trapp B, Fairchild R, Colmenares C, Silverman RH. Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L. EMBO J. 1997 Nov 3;16(21):6355-63. PubMed PMID: 9351818; PubMed Central PMCID: PMC1170242.

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