Synonym
Butocarboxim; CO 755; Drawin 755;
IUPAC/Chemical Name
2-Butanone, 3-(methylthio)-, O-(N-methylcarbamoyl)oxime
InChi Key
SFNPDDSJBGRXLW-WEVVVXLNSA-N
InChi Code
InChI=1S/C7H14N2O2S/c1-5(6(2)12-4)9-11-7(10)8-3/h6H,1-4H3,(H,8,10)/b9-5+
SMILES Code
C/C(C(SC)C)=N\OC(NC)=O
Purity
>98% (mixture of isomers)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
190.26
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Fang Q, Wang L, Hua X, Wang Y, Wang S, Cheng Q, Cai J, Liu F. An enzyme- linked chemiluminescent immunoassay developed for detection of Butocarboxim from agricultural products based on monoclonal antibody. Food Chem. 2015 Jan 1;166:372-379. doi: 10.1016/j.foodchem.2014.06.060. Epub 2014 Jun 18. PMID: 25053070.
2: Yamagishi Y, Nagasawa S, Iwase H, Ogra Y. Evaluation of Post-Mortem Interaction between Hemoglobin and Oxime-Type Carbamate Pesticides. Chem Res Toxicol. 2022 Jun 20;35(6):1110-1116. doi: 10.1021/acs.chemrestox.2c00092. Epub 2022 May 13. PMID: 35559618.
3: Garcia-Marí F, Soto A. Monitoring butocarboxim resistance of the woolly whitefly (Homoptera: Aleyrodidae) in citrus from Valencia, Spain. J Econ Entomol. 2001 Dec;94(6):1558-63. doi: 10.1093/jee/94.6.1558. PMID: 11777064.
4: Hou C, Wang Z, Li X, Bai Y, Chai J, Li X, Gao J, Xu H. Study of modeling and optimization for predicting the acute toxicity of carbamate pesticides using the binding information with carrier protein. Spectrochim Acta A Mol Biomol Spectrosc. 2022 May 15;273:121038. doi: 10.1016/j.saa.2022.121038. Epub 2022 Feb 15. PMID: 35189491.
5: Di Corcia A, Nazzari M, Rao R, Samperi R, Sebastiani E. Simultaneous determination of acidic and non-acidic pesticides in natural waters by liquid chromatography-mass spectrometry. J Chromatogr A. 2000 May 5;878(1):87-98. doi: 10.1016/s0021-9673(00)00263-6. PMID: 10843548.
6: Catalá-Icardo M, Meseguer-Lloret S, Torres-Cartas S. Photoinduced chemiluminescence determination of carbamate pesticides. Photochem Photobiol Sci. 2016 May 11;15(5):626-34. doi: 10.1039/c6pp00056h. Epub 2016 Apr 15. PMID: 27079156.
7: Leandro CC, Hancock P, Fussell RJ, Keely BJ. Ultra-performance liquid chromatography for the determination of pesticide residues in foods by tandem quadrupole mass spectrometry with polarity switching. J Chromatogr A. 2007 Mar 16;1144(2):161-9. doi: 10.1016/j.chroma.2007.01.030. Epub 2007 Jan 13. PMID: 17303144.
8: Bogialli S, Curini R, Di Corcia A, Laganà A, Nazzari M, Tonci M. Simple and rapid assay for analyzing residues of carbamate insecticides in bovine milk: hot water extraction followed by liquid chromatography-mass spectrometry. J Chromatogr A. 2004 Oct 29;1054(1-2):351-7. doi: 10.1016/j.chroma.2004.04.014. PMID: 15553162.
9: Aharonson N, Muszkat L. Direct gas chromatographic determination of the two isomeric insecticides, aldicarb and butocarboxime and their toxic metabolites: application to residue analysis in crops and leaves. Z Lebensm Unters Forsch. 1985 Feb;180(2):96-100. doi: 10.1007/BF01042631. PMID: 3984517.