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MedKoo Cat#: 596529 | Name: L 363851

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 363851 is a Neurokinin B agonist.

Chemical Structure

L 363851
L 363851
CAS#111608-31-2

Theoretical Analysis

MedKoo Cat#: 596529

Name: L 363851

CAS#: 111608-31-2

Chemical Formula: C38H51N6O7S

Exact Mass: 735.3540

Molecular Weight: 735.92

Elemental Analysis: C, 62.02; H, 6.99; N, 11.42; O, 15.22; S, 4.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
L 363851; L-363851; L363851; L-363,851; L 363,851; L363,851;
IUPAC/Chemical Name
(2S)-2-((3R)-3-(((S)-3-amino-3,4-dioxo-4-((S)-5-oxopyrrolidin-2-yl)-1-phenyl-3l5-butan-2-yl)phenylalanyl)-2-oxopyrrolidin-1-yl)-N-((S)-1-amino-4-(methylthio)-1-oxobutan-2-yl)-4-methylpentanamide
InChi Key
VAHXHCYEUTVAJU-XBNFHRNPSA-N
InChi Code
InChI=1S/C38H51N6O7S/c1-23(2)20-30(36(49)43-28(35(39)48)17-19-52-3)44-18-16-26(37(44)50)33(46)29(21-24-10-6-4-7-11-24)41-31(22-25-12-8-5-9-13-25)38(40,51)34(47)27-14-15-32(45)42-27/h4-13,23,26-31,41H,14-22H2,1-3H3,(H2,39,48)(H2,40,51)(H,42,45)(H,43,49)/t26-,27+,28+,29?,30+,31+/m1/s1
SMILES Code
O=C(N)(C([C@H](CC1)NC1=O)=O)[C@H](CC2=CC=CC=C2)NC(CC3=CC=CC=C3)C([C@@H]4C(N([C@H](C(N[C@H](C(N)=O)CCSC)=O)CC(C)C)CC4)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 735.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Grandordy BM, Frossard N, Rhoden KJ, Barnes PJ. Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction. Mol Pharmacol. 1988 May;33(5):515-9. PubMed PMID: 2452969. 2: Stoessl AJ, Dourish CT, Young SC, Williams BJ, Iversen SD, Iversen LL. Senktide, a selective neurokinin B-like agonist, elicits serotonin-mediated behaviour following intracisternal administration in the mouse. Neurosci Lett. 1987 Oct 5;80(3):321-6. PubMed PMID: 2446214.