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MedKoo Cat#: 558057 | Name: Sodium cacodylate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sodium cacodylate is an arsenical that has been used as a dermatologic agent and as an herbicide.

Chemical Structure

Sodium cacodylate
Sodium cacodylate
CAS#124-65-2

Theoretical Analysis

MedKoo Cat#: 558057

Name: Sodium cacodylate

CAS#: 124-65-2

Chemical Formula: C2H6AsNaO2

Exact Mass:

Molecular Weight: 159.98

Elemental Analysis: C, 15.02; H, 3.78; As, 46.83; Na, 14.37; O, 20.00

Price and Availability

Size Price Availability Quantity
10g USD 230.00
25g USD 370.00
100g USD 680.00
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Related CAS #
No Data
Synonym
Arsicodile; Arsine oxide, hydroxydimethyl-, sodium salt; Arsinic acid, dimethyl-, sodium salt; Arsycodile; Arsysodila; Bolate; Bolls-eye;
IUPAC/Chemical Name
Arsinic acid, dimethyl-, sodium salt
InChi Key
IHQKEDIOMGYHEB-UHFFFAOYSA-M
InChi Code
InChI=1S/C2H7AsO2.Na/c1-3(2,4)5;/h1-2H3,(H,4,5);/q;+1/p-1
SMILES Code
C[As](C)([O-])=O.[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 159.98 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Weakley BS. How dangerous is sodium cacodylate? J Microsc. 1977 Mar;109(2):249-51. PubMed PMID: 875010. 2: Alemayehu S, Fish DJ, Brewood GP, Horne MT, Manyanga F, Dickman R, Yates I, Benight AS. Influence of buffer species on the thermodynamics of short DNA duplex melting: sodium phosphate versus sodium cacodylate. J Phys Chem B. 2009 Mar 5;113(9):2578-86. PubMed PMID: 19708201. 3: MCALPINE JC. HISTOCHEMICAL DEMONSTRATION OF THE ACTIVATION OF RAT ACETYLCHOLINESTERASE BY SODIUM CACODYLATE AND CACODYLIC ACID USING THE THIOACETIC ACID METHOD. J R Microsc Soc. 1963 Oct;82:95-106. PubMed PMID: 14328462. 4: STAUFFER VD. Sodium cacodylate and arsenic trioxide in anaplasmosis of cattle. North Am Vet. 1947 Apr;28(4):219-21. PubMed PMID: 20290871. 5: CRESSMAN EH. Pityriasis rosea; treatment with sodium cacodylate. J Am Osteopath Assoc. 1946 Jul;45:519. PubMed PMID: 20991141. 6: Song SH, Asher SA. Internal intensity standards for heme protein UV resonance Raman studies: excitation profiles of cacodylic acid and sodium selenate. Biochemistry. 1991 Feb 5;30(5):1199-205. PubMed PMID: 1846749. 7: McCoy CR, Stadelman BS, Brumaghim JL, Liu JT, Bain LJ. Arsenic and Its Methylated Metabolites Inhibit the Differentiation of Neural Plate Border Specifier Cells. Chem Res Toxicol. 2015 Jul 20;28(7):1409-21. doi: 10.1021/acs.chemrestox.5b00036. Epub 2015 Jun 10. PubMed PMID: 26024302. 8: Arnold LL, Suzuki S, Yokohira M, Kakiuchi-Kiyota S, Pennington KL, Cohen SM. Time course of urothelial changes in rats and mice orally administered arsenite. Toxicol Pathol. 2014 Jul;42(5):855-62. doi: 10.1177/0192623313489778. Epub 2013 May 20. PubMed PMID: 23690446. 9: Ghose BB. Sodium Cacodylate in the Treatment of Boils. Ind Med Gaz. 1928 Oct;63(10):607. PubMed PMID: 29011525; PubMed Central PMCID: PMC5235567. 10: Seno S, Tsujii T, Ono T, Ukita S. Cationic cacodylate iron colloid for the detection of anionic sites on cell surface and the histochemical stain of acid mucopolysaccharides. Histochemistry. 1983;78(1):27-31. PubMed PMID: 6223903. 11: Leake WH. THE INTRAVENOUS USE OF SODIUM CACODYLATE, MERCUROCHROME-220 SOLUBLE, AND GENTIAN VIOLET IN MALIGNANT ENDOCARDITIS. Cal West Med. 1926 Sep;25(3):346-9. PubMed PMID: 18740094; PubMed Central PMCID: PMC1655224. 12: Lennartson A, Håkansson M. Investigation of commercial sodium cacodylate trihydrate: penta-mu-aqua-disodium(I) bis(dimethylarsenate) and di-mu-aqua-bis[triaquasodium(I)] bis(dimethylarsenate). Acta Crystallogr C. 2008 Jan;64(Pt 1):m13-6. doi: 10.1107/S0108270107055151. Epub 2007 Dec 14. PubMed PMID: 18216428. 13: Li H, Lin J, Li Y, Yan J, Li B, Zhang W, Dong Z, Chen C. [Distribution of arsenic species and its DNA damage in subchronic arsenite-exposed mice]. Wei Sheng Yan Jiu. 2013 Sep;42(5):764-9, 776. Chinese. PubMed PMID: 24218882. 14: Fujioka M, Gi M, Kawachi S, Tatsumi K, Ishii N, Doi K, Kakehashi A, Wanibuchi H. Examination of in vivo mutagenicity of sodium arsenite and dimethylarsinic acid in gpt delta rats. J Environ Sci (China). 2016 Nov;49:125-130. doi: 10.1016/j.jes.2016.07.005. Epub 2016 Jul 30. PubMed PMID: 28007167. 15: Chen B, Lu X, Arnold LL, Cohen SM, Le XC. Identification of Methylated Dithioarsenicals in the Urine of Rats Fed with Sodium Arsenite. Chem Res Toxicol. 2016 Sep 19;29(9):1480-7. doi: 10.1021/acs.chemrestox.6b00151. Epub 2016 Aug 8. PubMed PMID: 27463804. 16: Wu H, Krishnamohan M, Lam PK, Ng JC. Urinary arsenic speciation profiles in mice subchronically exposed to low concentrations of sodium arsenate in drinking water. Kaohsiung J Med Sci. 2011 Sep;27(9):417-23. doi: 10.1016/j.kjms.2011.05.010. Epub 2011 Aug 23. PubMed PMID: 21914530. 17: Suzuki S, Arnold LL, Pennington KL, Kakiuchi-Kiyota S, Cohen SM. Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium. Toxicology. 2009 Jun 30;261(1-2):41-6. doi: 10.1016/j.tox.2009.04.042. Epub 2009 May 3. PubMed PMID: 19397947. 18: Mallannah S. The Uses of Sodium Cacodylate. Ind Med Gaz. 1921 Mar;56(3):96-97. PubMed PMID: 29007205; PubMed Central PMCID: PMC5166255. 19: Levinson HS, Garber EB. Radiation dosimetry with sodium cacodylate and tris. Nature. 1965 Aug 14;207(998):751-2. PubMed PMID: 5885917. 20: Zhao F, Wang Y, Jin Y, Zhong Y, Yu X, Li G, Lv X, Sun G. Effects of exogenous methionine on arsenic burden and NO metabolism in brain of mice exposed to arsenite through drinking water. Environ Toxicol. 2012 Dec;27(12):700-6. doi: 10.1002/tox.20689. Epub 2011 May 10. PubMed PMID: 21560223.