MedKoo Cat#: 591286 | Name: Proxazole citrate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Proxazole Citrate is a spasmolytic papaverine-like agent used for functional gastrointestinal disorders in veterinary and acute renal insufficiency.

Chemical Structure

Proxazole citrate
Proxazole citrate
CAS#132-35-4

Theoretical Analysis

MedKoo Cat#: 591286

Name: Proxazole citrate

CAS#: 132-35-4

Chemical Formula: C23H33N3O8

Exact Mass: 479.2268

Molecular Weight: 479.53

Elemental Analysis: C, 57.61; H, 6.94; N, 8.76; O, 26.69

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Proxazole citrate; NSC 303872; NSC-303872; NSC303872;
IUPAC/Chemical Name
1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-(alpha-ethylbenzyl)-, citrate
InChi Key
WFAULHLDTDDABL-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H25N3O.C6H8O7/c1-4-15(14-10-8-7-9-11-14)17-18-16(21-19-17)12-13-20(5-2)6-3;7-3(8)1-6(13,5(11)12)2-4(9)10/h7-11,15H,4-6,12-13H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
SMILES Code
CCC(C1=NOC(CCN(CC)CC)=N1)C2=CC=CC=C2.OC(C(O)=O)(CC(O)=O)CC(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 479.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Rondinelli M, Suma V, Casara D, Zonzin G. Effects of the treatment with proxazole citrate on the utero-placental blood flow of patients affected by EPH-gestosis. Bibl Anat. 1979;(18):274-6. PubMed PMID: 496846. 2: Maselli G, Delli Colli R, Donadio C. [Proxazole citrate in labor]. Patol Clin Ostet Ginecol. 1977 Jul-Aug;5(4):200-8. Italian. PubMed PMID: 606606. 3: Calabrese L, Macchini M. Study on the action of proxazole citrate on gastric blood supply. Endoscopic findings in elderly patients. Arzneimittelforschung. 1972 Apr;22(4):763-8. PubMed PMID: 5068257.