Synonym
Hexapropymate; Esapropimato; Lunamin; L 2103; L-2103; L2103; NSC 169094; NSC-169094; NSC169094;
IUPAC/Chemical Name
1-(prop-2-yn-1-yl)cyclohexyl carbamate
InChi Key
MIRHIEAGDGUXKL-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H15NO2/c1-2-6-10(13-9(11)12)7-4-3-5-8-10/h1H,3-8H2,(H2,11,12)
SMILES Code
NC(OC1(CC#C)CCCCC1)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
181.23
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Gustafsson LL, Berg A, Magnusson A, Malmlund HO, Sandell BM, Stig R. Hexapropymate self-poisoning causes severe and long-lasting clinical symptoms. Med Toxicol Adverse Drug Exp. 1989 Jul-Aug;4(4):295-301. PubMed PMID: 2770531.
2: Leyssens L, van Boven M, Daenens P. Biotransformation of hexapropymate in man. Part 2: Isolation and identification of metabolites. Pharmazie. 1984 Feb;39(2):114-7. PubMed PMID: 6718477.
3: Robbins G, Brown AK. Hexapropymate self-poisoning. Br Med J. 1978 Jun 17;1(6127):1593. PubMed PMID: 656827; PubMed Central PMCID: PMC1605342.
4: Hassoun A, van Binst R, Vandendriessche M. [A rapid and simple method for the qualitative and quantitative determination of hexapropymate in biological fluids and organs (author's transl)]. Toxicol Eur Res. 1978 May;1(3):185-8. French. PubMed PMID: 741478.
5: Risberg AM, Risberg J, Ingvar DH. [Effects of hexapropymate on sleep in normal humans, measured with a polygraphic method]. Sem Hop Ther. 1975 Feb;51(2):99-104. French. PubMed PMID: 1099650.
6: Siguier F, Godeau P, Vergoz D, Imbert JC, Herreman G, Reinert P. [Immuno-allergic thrombopenic purpura caused by hexapropymate sensitization]. Ann Med Interne (Paris). 1971 Mar;122(3):435-8. French. PubMed PMID: 5314641.
7: Favarel-Garrigues B, Bourgeois M, Vincent JD. [Polygraphic study of night sleep under the effects of hexapropymate]. Bord Med. 1971 Jan;4(1):255-8 passim. French. PubMed PMID: 5553039.
8: Noirfalise A. [5 cases of suspected hexapropymate poisoning]. Eur J Toxicol. 1971 Jan-Feb;4(1):50-2. French. PubMed PMID: 5092668.
9: Favarel-Garrigue B, Bourgeois M. [Polygraphic study of night sleep under hexapropymate]. Presse Med. 1970 Nov 21;78(49):2201-2. French. PubMed PMID: 4320460.
10: CANLORBE P, BORNICHE P. [Pediatric indications for a synthetic non-barbituric hypnotic: hexapropymate]. Ann Pediatr (Paris). 1962 Dec 2;9:632-3. French. PubMed PMID: 14018306.
