MedKoo Cat#: 562899 | Name: IWP-3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IWP-3 is an inactivator of Porcn function. It acts by inhibiting Wnt production.

Chemical Structure

IWP-3
IWP-3
CAS#687561-60-0

Theoretical Analysis

MedKoo Cat#: 562899

Name: IWP-3

CAS#: 687561-60-0

Chemical Formula: C22H17FN4O2S3

Exact Mass: 484.0498

Molecular Weight: 484.58

Elemental Analysis: C, 54.53; H, 3.54; F, 3.92; N, 11.56; O, 6.60; S, 19.85

Price and Availability

Size Price Availability Quantity
5mg USD 310.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
IWP-3; IWP 3; IWP3;
IUPAC/Chemical Name
2-[[3-(4-Fluorophenyl)-3,4,6,7-tetrahydro-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-N-(6-methyl-2-benzothiazolyl)-acetamide
InChi Key
XVMHQSDMKWQNBK-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H17FN4O2S3/c1-12-2-7-15-17(10-12)32-21(24-15)26-18(28)11-31-22-25-16-8-9-30-19(16)20(29)27(22)14-5-3-13(23)4-6-14/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)
SMILES Code
O=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=C(F)C=C5)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 484.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tian Z, Yang G, Jiang P, Zhang L, Wang J, Sun S. Long non-coding RNA Sox4 promotes proliferation and migration by activating Wnt/β-catenin signaling pathway in osteosarcoma. Pharmazie. 2017 Sep 1;72(9):537-542. doi: 10.1691/ph.2017.7548. PubMed PMID: 29441981.