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MedKoo Cat#: 591282 | Name: AF 399

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AF 399 is a CCR4 antagonist. it reverses the tumor promoting environment.

Chemical Structure

AF 399
AF 399
CAS# 91533-02-7

Theoretical Analysis

MedKoo Cat#: 591282

Name: AF 399

CAS#: 91533-02-7

Chemical Formula: C12H17N3O3S

Exact Mass: 283.0991

Molecular Weight: 283.35

Elemental Analysis: C, 50.87; H, 6.05; N, 14.83; O, 16.94; S, 11.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AF 399; AF-399; AF399
IUPAC/Chemical Name
Sulfanilamide, N4-(alpha-pyrrolidinoacetyl)-
InChi Key
CRDXWPKUELSCSF-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H17N3O3S/c13-19(17,18)11-5-3-10(4-6-11)14-12(16)9-15-7-1-2-8-15/h3-6H,1-2,7-9H2,(H,14,16)(H2,13,17,18)
SMILES Code
NS(=O)(C1=CC=C(NC(CN2CCCC2)=O)C=C1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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Arch Gerontol Geriatr. 2016 Jul-Aug;65:248-54. doi: 10.1016/j.archger.2016.04.008. Epub 2016 Apr 13. PubMed PMID: 27131228. 15: Yavuz B, Ayturk M, Ozkan S, Ozturk M, Topaloglu C, Aksoy H, Şabanoglu C, Tanalp AC, Dal K, Ata N, Yavuz BB. A real world data of dabigatran etexilate: multicenter registry of oral anticoagulants in nonvalvular atrial fibrillation. J Thromb Thrombolysis. 2016 Oct;42(3):399-404. doi: 10.1007/s11239-016-1361-4. PubMed PMID: 27085540. 16: Gong Y, Qi M, Chen J, Fang R, Mai C, Chen T, Tang H, Tang Y. XRCC1 Arg194Trp and Arg399Gln polymorphisms and risk of extrahepatic cholangiocarcinoma: a hospital-based case-control study in China. Int J Clin Exp Med. 2015 Oct 15;8(10):19339-45. eCollection 2015. 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