MedKoo Cat#: 562882 | Name: 50F10

Description:

WARNING: This product is for research use only, not for human or veterinary use.

50F10 is a stabilizer of the active LPL dimer. It acts by preventing both angptl4- and heat-induced inactivation of LPL and reducing postprandial triglyceride levels.

Chemical Structure

50F10
50F10
CAS#690689-90-8

Theoretical Analysis

MedKoo Cat#: 562882

Name: 50F10

CAS#: 690689-90-8

Chemical Formula: C28H25N3O5

Exact Mass: 483.1794

Molecular Weight: 483.52

Elemental Analysis: C, 69.55; H, 5.21; N, 8.69; O, 16.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
50F10; 50-F-10; 50 F 10;
IUPAC/Chemical Name
2,3-Dihydro-2-[3-[[(4-methylphenyl)amino]carbonyl]-4-(1-piperidinyl)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid
InChi Key
BRZAMKDHLIXUND-UHFFFAOYSA-N
InChi Code
InChI=1S/C28H25N3O5/c1-17-5-8-19(9-6-17)29-25(32)23-16-20(10-12-24(23)30-13-3-2-4-14-30)31-26(33)21-11-7-18(28(35)36)15-22(21)27(31)34/h5-12,15-16H,2-4,13-14H2,1H3,(H,29,32)(H,35,36)
SMILES Code
O=C(C1=CC2=C(C(N(C3=CC=C(N4CCCCC4)C(C(NC5=CC=C(C)C=C5)=O)=C3)C2=O)=O)C=C1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 483.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Larsson M, Caraballo R, Ericsson M, Lookene A, Enquist PA, Elofsson M, Nilsson SK, Olivecrona G. Identification of a small molecule that stabilizes lipoprotein lipase in vitro and lowers triglycerides in vivo. Biochem Biophys Res Commun. 2014 Jul 25;450(2):1063-9. doi: 10.1016/j.bbrc.2014.06.114. Epub 2014 Jun 28. PubMed PMID: 24984153.