MedKoo Cat#: 591265 | Name: Ticarcillin free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ticarcillin disodium is an antibiotic derived from penicillin similar to Carbenicillin in action.

Chemical Structure

Ticarcillin free base
Ticarcillin free base
CAS#34787-01-4

Theoretical Analysis

MedKoo Cat#: 591265

Name: Ticarcillin free base

CAS#: 34787-01-4

Chemical Formula: C15H16N2O6S2

Exact Mass: 384.0450

Molecular Weight: 384.42

Elemental Analysis: C, 46.87; H, 4.20; N, 7.29; O, 24.97; S, 16.68

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Ticarcillin free base
IUPAC/Chemical Name
4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((carboxy-3-thienylacetyl)amino)-3,3-dimethyl-7-oxo-, (2S-(2alpha,5alpha,6beta(S*)))-
InChi Key
OHKOGUYZJXTSFX-KZFFXBSXSA-N
InChi Code
1S/C15H16N2O6S2/c1-15(2)9(14(22)23)17-11(19)8(12(17)25-15)16-10(18)7(13(20)21)6-3-4-24-5-6/h3-5,7-9,12H,1-2H3,(H,16,18)(H,20,21)(H,22,23)/t7-,8-,9+,12-/m1/s1
SMILES Code
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)[C@@H](c3ccsc3)C(=O)O)C(=O)O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yabalak E. Degradation of ticarcillin by subcritial water oxidation method: Application of response surface methodology and artificial neural network modeling. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2018 May 18:1-11. doi: 10.1080/10934529.2018.1471023. [Epub ahead of print] PubMed PMID: 29775394. 2: Kaczmarek A, Skowron K, Budzyńska A, Gospodarek-Komkowska E. Virulence-associated genes and antibiotic susceptibility among vaginal and rectal Escherichia coli isolates from healthy pregnant women in Poland. Folia Microbiol (Praha). 2018 Apr 12. doi: 10.1007/s12223-018-0598-z. [Epub ahead of print] PubMed PMID: 29644511. 3: Zhao J, Liu Y, Liu Y, Wang D, Ni W, Wang R, Liu Y, Zhang B. Frequency and Genetic Determinants of Tigecycline Resistance in Clinically Isolated Stenotrophomonas maltophilia in Beijing, China. Front Microbiol. 2018 Mar 26;9:549. doi: 10.3389/fmicb.2018.00549. eCollection 2018. PubMed PMID: 29632524; PubMed Central PMCID: PMC5879106. 4: Grispoldi L, Bertero F, Franceschini S, Mastrosimone F, Sechi P, Iulietto MF, Ceccarelli M, Cenci-Goga BT. Prevalence and characterisation of shigatoxigenic Escherichia coli isolated from beef cattle fed with prebiotics. Ital J Food Saf. 2017 Dec 14;6(4):6958. doi: 10.4081/ijfs.2017.6958. eCollection 2017 Oct 20. PubMed PMID: 29564239; PubMed Central PMCID: PMC5850057. 5: Spierer O, Miller D, O'Brien TP. Comparative activity of antimicrobials against Pseudomonas aeruginosa, Achromobacter xylosoxidans and Stenotrophomonas maltophilia keratitis isolates. Br J Ophthalmol. 2018 May;102(5):708-712. doi: 10.1136/bjophthalmol-2017-311751. Epub 2018 Feb 19. PubMed PMID: 29459431. 6: Peng F, Zhong LL, Lin XJ, Chen M, Zhou M. [Burkholderia cepacia infection in children: a clinical analysis of 16 cases]. Zhongguo Dang Dai Er Ke Za Zhi. 2018 Feb;20(2):112-115. Chinese. PubMed PMID: 29429458. 7: Schiavano GF, Carloni E, Andreoni F, Magi S, Chironna M, Brandi G, Amagliani G. Prevalence and antibiotic resistance of Pseudomonas aeruginosa in water samples in central Italy and molecular characterization of oprD in imipenem resistant isolates. PLoS One. 2017 Dec 6;12(12):e0189172. doi: 10.1371/journal.pone.0189172. eCollection 2017. PubMed PMID: 29211780; PubMed Central PMCID: PMC5718518. 8: Ben Nejma M, Sioud O, Mastouri M. Quinolone-resistant clinical strains of Pseudomonas aeruginosa isolated from University Hospital in Tunisia. 3 Biotech. 2018 Jan;8(1):1. doi: 10.1007/s13205-017-1019-8. Epub 2017 Nov 13. PubMed PMID: 29201587; PubMed Central PMCID: PMC5688038. 9: Stachelska MA. Determining the prevalence of inv-positive and ail-positive Yersinia enterocolitica in pig tonsils using PCR and culture methods. Acta Sci Pol Technol Aliment. 2017 Jul-Sep;16(3):303-310. doi: 10.17306/J.AFS.0495. PubMed PMID: 29055978. 10: Yousfi M, Touati A, Muggeo A, Mira B, Asma B, Brasme L, Guillard T, de Champs C. Clonal dissemination of OXA-48-producing Enterobacter cloacae isolates from companion animals in Algeria. J Glob Antimicrob Resist. 2018 Mar;12:187-191. doi: 10.1016/j.jgar.2017.10.007. Epub 2017 Oct 16. PubMed PMID: 29042339. 11: Lefeuvre S, Bois-Maublanc J, Hocqueloux L, Bret L, Francia T, Eleout-Da Violante C, Billaud EM, Barbier F, Got L. A simple ultra-high-performance liquid chromatography-high resolution mass spectrometry assay for the simultaneous quantification of 15 antibiotics in plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Oct 15;1065-1066:50-58. doi: 10.1016/j.jchromb.2017.09.014. Epub 2017 Sep 11. PubMed PMID: 28946125. 12: Rasmussen C, Allender MC, Phillips CA, Byrd J, Lloyd T, Maddox C. MULTI-DRUG RESISTANCE PATTERNS OF ENTERIC BACTERIA IN TWO POPULATIONS OF FREE-RANGING EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA). J Zoo Wildl Med. 2017 Sep;48(3):708-715. doi: 10.1638/2016-0194.1. PubMed PMID: 28920793. 13: Guermazi-Toumi S, Boujlel S, Assoudi M, Issaoui R, Tlili S, Hlaiem ME. Susceptibility profiles of bacteria causing urinary tract infections in Southern Tunisia. J Glob Antimicrob Resist. 2018 Mar;12:48-52. doi: 10.1016/j.jgar.2017.09.004. Epub 2017 Sep 14. PubMed PMID: 28918351. 14: Alexandre K, Fantin B. Pharmacokinetics and Pharmacodynamics of Temocillin. Clin Pharmacokinet. 2018 Mar;57(3):287-296. doi: 10.1007/s40262-017-0584-7. Review. PubMed PMID: 28849402. 15: Wu WX, Liu D, Wang YW, Wang C, Yang C, Liu XZ, Mai LF, Ren M, Yan L. Empirical Antibiotic Treatment in Diabetic Foot Infection: A Study Focusing on the Culture and Antibiotic Sensitivity in a Population From Southern China. Int J Low Extrem Wounds. 2017 Sep;16(3):173-182. doi: 10.1177/1534734617725410. Epub 2017 Aug 24. PubMed PMID: 28836481. 16: Deshayes S, Coquerel A, Verdon R. Neurological Adverse Effects Attributable to β-Lactam Antibiotics: A Literature Review. Drug Saf. 2017 Dec;40(12):1171-1198. doi: 10.1007/s40264-017-0578-2. Review. PubMed PMID: 28755095. 17: Paterson S. Brainstem auditory evoked responses in 37 dogs with otitis media before and after topical therapy. J Small Anim Pract. 2018 Jan;59(1):10-15. doi: 10.1111/jsap.12711. Epub 2017 Jul 18. PubMed PMID: 28718886. 18: Rahim F, Ullah F, Ishfaq M, Afridi AK, Rahman SU, Rahman H. Frequency Of Common Bacteria And Their Antibiotic Sensitivity Pattern In Diabetics Presenting With Foot Ulcer. J Ayub Med Coll Abbottabad. 2016 Jul-Sep;28(3):528-533. PubMed PMID: 28712228. 19: Godič Torkar K, Dražetić M. The microbial contamination and the presence of β-lactamase producing Gram-negative bacteria in the water and on the surfaces of public recreation water facilities. Int J Environ Health Res. 2017 Aug;27(4):293-305. doi: 10.1080/09603123.2017.1342227. Epub 2017 Jun 20. PubMed PMID: 28631499. 20: Dortet L, Bernabeu S, Gonzalez C, Naas T. Comparison of Two Phenotypic Algorithms To Detect Carbapenemase-Producing Enterobacteriaceae. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00796-17. doi: 10.1128/AAC.00796-17. Print 2017 Aug. PubMed PMID: 28607010; PubMed Central PMCID: PMC5527584.