L 1935| CAS#13957-35-2 | histamine-liberator

MedKoo Cat#: 596406 | Name: L 1935

Description:

WARNING: This product is for research use only, not for human or veterinary use.

L 1935 is a powerful histamine-liberator.

Chemical Structure

L 1935

CAS#13957-35-2

Theoretical Analysis

MedKoo Cat#: 596406

Name: L 1935

CAS#: 13957-35-2

Chemical Formula: C17H21NO2

Exact Mass: 271.1572

Molecular Weight: 271.36

Elemental Analysis: C, 75.25; H, 7.80; N, 5.16; O, 11.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

L 1935; Histamine-liberator L 1935; Compound l1935; L-1935; L1935;

IUPAC/Chemical Name

4-(3-amino-1-(4-hydroxyphenyl)butyl)-2-methylphenol

InChi Key

QQXUACLYCIWJIU-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H21NO2/c1-11-9-14(5-8-17(11)20)16(10-12(2)18)13-3-6-15(19)7-4-13/h3-9,12,16,19-20H,10,18H2,1-2H3

SMILES Code

OC1=CC=C(C(C2=CC=C(O)C=C2)CC(N)C)C=C1C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 271.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kumar GC, Bhuvana K, Venkatarathnamma PN, Sarala N. Serum creatine phosphokinase as predictor of intermediate syndrome in organophosphorus poisoning. Indian J Crit Care Med. 2015 Jul;19(7):384-7. doi: 10.4103/0972-5229.160274. PubMed PMID: 26180430; PubMed Central PMCID: PMC4502490. 2: Gill SJ, Robert CH, Coletta M, Di Cera E, Brunori M. Cooperative free energies for nested allosteric models as applied to human hemoglobin. Biophys J. 1986 Oct;50(4):747-52. PubMed PMID: 3779009; PubMed Central PMCID: PMC1329852. 3: Lecomte J. [Respective role of endogenous histamine and 5-hydroxytryptamine in vascular collapse induced in rats by L 1935]. C R Seances Soc Biol Fil. 1966;160(6):1343-6. French. PubMed PMID: 4381696. 4: RADERMECKER M. [THE INFLUENCE OF AN INHIBITOR OF HISTIDINE DECARBOXYLASE ON HISTAMINE LIBERATION PRODUCED IN MAN BY THE INTRADERMAL INJECTION OF L 1935 AND THE LOCAL ANAPHYLACTIC REACTION]. Acta Allergol. 1965;20:77-83. French. PubMed PMID: 14311532. 5: LECOMTE J, MELON J, PETIT JM. [L 1935, a powerful histamine-liberator, is shown to be without effect on human broncho-pulmonary tissues]. Rev Belg Pathol Med Exp. 1960 Oct;27:212-8. French. PubMed PMID: 13760118. 6: BRANELLEC A, BRIOT M, HALPERN BN, LIACOPOULOS P, NEVEU T. [Histamine-liberating properties of a substituted butylamine (L 1935) in dogs]. C R Seances Soc Biol Fil. 1956;150(7):1302-6. French. PubMed PMID: 13397054. 7: FELDBERG W, LECOMTE J. Release of histamine by a substituted butylamine (L 1935): comparison with compound 48/80. Br J Pharmacol Chemother. 1955 Jun;10(2):254-9. PubMed PMID: 14389669; PubMed Central PMCID: PMC1509492.