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MedKoo Cat#: 562876 | Name: CID-5056270
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CID-5056270 is an inhibitor of ROCK2 enzymatic activity.

Chemical Structure

CID-5056270
CID-5056270
CAS#681173-76-2

Theoretical Analysis

MedKoo Cat#: 562876

Name: CID-5056270

CAS#: 681173-76-2

Chemical Formula: C17H13N3O3S

Exact Mass: 339.0678

Molecular Weight: 339.36

Elemental Analysis: C, 60.17; H, 3.86; N, 12.38; O, 14.14; S, 9.45

Price and Availability

Size Price Availability Quantity
10mg USD 750.00 2 Weeks
50mg USD 1,650.00 2 Weeks
500mg USD 3,950.00 2 Weeks
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Related CAS #
No Data
Synonym
CID-5056270; CID 5056270; CID5056270;
IUPAC/Chemical Name
N-(4-Pyridin-4-yl-1,3-thiazol-2-yl)-2,3-dihydro-1,4-benzodioxine-3-carboxamide
InChi Key
QKKGSTFAKMXWFE-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H13N3O3S/c21-16(15-9-22-13-3-1-2-4-14(13)23-15)20-17-19-12(10-24-17)11-5-7-18-8-6-11/h1-8,10,15H,9H2,(H,19,20,21)
SMILES Code
O=C(C1COC2=CC=CC=C2O1)NC3=NC(C4=CC=NC=C4)=CS3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 339.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Feng Y, Yin Y, Weiser A, Griffin E, Cameron MD, Lin L, Ruiz C, Schürer SC, Inoue T, Rao PV, Schröter T, Lograsso P. Discovery of substituted 4-(pyrazol-4-yl)-phenylbenzodioxane-2-carboxamides as potent and highly selective Rho kinase (ROCK-II) inhibitors. J Med Chem. 2008 Nov 13;51(21):6642-5. doi: 10.1021/jm800986w. Epub 2008 Oct 4. PMID: 18834107; PMCID: PMC3708311.