4'-Azidothymidine 5'-triphosphate | CAS#140158-13-0 |

MedKoo Cat#: 591221 | Name: 4'-Azidothymidine 5'-triphosphate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

4'-Azidothymidine 5'-triphosphate has selective action on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta.

Chemical Structure

4'-Azidothymidine 5'-triphosphate

CAS#140158-13-0

Theoretical Analysis

MedKoo Cat#: 591221

Name: 4'-Azidothymidine 5'-triphosphate

CAS#: 140158-13-0

Chemical Formula: C10H16N5O14P3

Exact Mass: 522.9907

Molecular Weight: 523.18

Elemental Analysis: C, 22.96; H, 3.08; N, 13.39; O, 42.81; P, 17.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

4'-Azidothymidine 5'-triphosphate; Adrt-TP; Adrt TP; AdrtTP

IUPAC/Chemical Name

4'-Azidothymidine 5'-triphosphate;

InChi Key

IWEKENYUWQNKCU-NYNCVSEMSA-N

InChi Code

InChI=1S/C10H16N5O14P3/c1-5-3-15(9(18)12-8(5)17)7-2-6(16)10(27-7,13-14-11)4-26-31(22,23)29-32(24,25)28-30(19,20)21/h3,6-7,16H,2,4H2,1H3,(H,22,23)(H,24,25)(H,12,17,18)(H2,19,20,21)/t6-,7+,10+/m0/s1

SMILES Code

O[C@@H](C[C@H](N1C(NC(C(C)=C1)=O)=O)O2)[C@@]2(N=[N+]=[N-])COP(O)(OP(O)(OP(O)(O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 523.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Chen MS, Suttmann RT, Papp E, Cannon PD, McRoberts MJ, Bach C, Copeland WC, Wang TS. Selective action of 4'-azidothymidine triphosphate on reverse transcriptase of human immunodeficiency virus type 1 and human DNA polymerases alpha and beta. Biochemistry. 1993 Jun 15;32(23):6002-10. PubMed PMID: 7685186.