p-Decylaminophenol | CAS#23227-12-5 | melanogenesis inhibitor

MedKoo Cat#: 562845 | Name: p-Decylaminophenol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

p-Decylaminophenol is an inhibitor of melanogenesis.

Chemical Structure

p-Decylaminophenol

CAS#23227-12-5

Theoretical Analysis

MedKoo Cat#: 562845

Name: p-Decylaminophenol

CAS#: 23227-12-5

Chemical Formula: C16H27NO

Exact Mass: 249.2093

Molecular Weight: 249.39

Elemental Analysis: C, 77.06; H, 10.91; N, 5.62; O, 6.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

p-Decylaminophenol; p Decylaminophenol; pDAP; p-DAP; p DAP;

IUPAC/Chemical Name

4-Decylamino-phenol

InChi Key

XOAJCTZLSXGBHZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H27NO/c1-2-3-4-5-6-7-8-9-14-17-15-10-12-16(18)13-11-15/h10-13,17-18H,2-9,14H2,1H3

SMILES Code

OC1=CC=C(NCCCCCCCCCC)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 249.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Takahashi N, Koyama S, Hasegawa S, Yamasaki M, Imai M. Anticancer efficacy of p-dodecylaminophenol against high-risk and refractory neuroblastoma cells in vitro and in vivo. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4664-4672. doi: 10.1016/j.bmcl.2017.09.005. Epub 2017 Sep 9. PubMed PMID: 28927789. 2: Takahashi N, Imai M, Komori Y. Inhibitory effects of p-alkylaminophenol on melanogenesis. Bioorg Med Chem. 2014 Sep 1;22(17):4677-83. doi: 10.1016/j.bmc.2014.07.016. Epub 2014 Jul 19. PubMed PMID: 25126713. 3: Komori Y, Imai M, Yamauchi T, Higashiyama K, Takahashi N. Effect of p-aminophenols on tyrosinase activity. Bioorg Med Chem. 2014 Aug 1;22(15):3994-4000. doi: 10.1016/j.bmc.2014.05.073. Epub 2014 Jun 11. PubMed PMID: 24972725. 4: Ohba T, Yamauch T, Higashiyama K, Takahashi N. Potent anticancer activities of novel aminophenol analogues against various cancer cell lines. Bioorg Med Chem. 2007 Jan 15;15(2):847-53. Epub 2006 Oct 25. PubMed PMID: 17092729. 5: Takahashi N, Ohba T, Yamauchi T, Higashiyama K. Antioxidant and anticancer activities of novel p-alkylaminophenols and p-acylaminophenols (aminophenol analogues). Bioorg Med Chem. 2006 Sep 1;14(17):6089-96. Epub 2006 May 24. PubMed PMID: 16725328.