Acth (4-10) | CAS#4037-01-8 | Melanocortin Receptor Agonist

MedKoo Cat#: 591213 | Name: Acth (4-10)

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ACTH (4-10) is a water soluble potent melanocortin receptor agonist.

Chemical Structure

Acth (4-10)

CAS#4037-01-8

Theoretical Analysis

MedKoo Cat#: 591213

Name: Acth (4-10)

CAS#: 4037-01-8

Chemical Formula: C44H59N13O10S

Exact Mass: 961.4229

Molecular Weight: 962.10

Elemental Analysis: C, 54.93; H, 6.18; N, 18.93; O, 16.63; S, 3.33

Price and Availability

Size	Price	Availability	Quantity
5mg	USD 350.00	2 Weeks
10mg	USD 550.00	2 Weeks

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Related CAS #

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Synonym

Acth (4-10); 4-10-Semax, ACTH - msh (4-10), Adrenocorticotropic hormone 4-10, Met-glu-his-phe-arg-trp-gly, Msh-acth (4-10),

IUPAC/Chemical Name

N-(N-(N(2)-(N-(N-(N-L-Methionyl-L-alpha-glutamyl)-L-histidyl)-L-phenylalanyl)-L-arginyl)-L-tryptophyl)glycine

InChi Key

HAAUASBAIUJHAN-LXOXETEGSA-N

InChi Code

InChI=1S/C44H59N13O10S/c1-68-17-15-29(45)38(62)53-32(13-14-36(58)59)41(65)57-35(20-27-22-48-24-52-27)43(67)55-33(18-25-8-3-2-4-9-25)42(66)54-31(12-7-16-49-44(46)47)40(64)56-34(39(63)51-23-37(60)61)19-26-21-50-30-11-6-5-10-28(26)30/h2-6,8-11,21-22,24,29,31-35,50H,7,12-20,23,45H2,1H3,(H,48,52)(H,51,63)(H,53,62)(H,54,66)(H,55,67)(H,56,64)(H,57,65)(H,58,59)(H,60,61)(H4,46,47,49)/t29-,31-,32-,33-,34-,35-/m0/s1

SMILES Code

O=C(O)CNC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CCCNC(N)=N)NC([C@H](CC3=CC=CC=C3)NC([C@H](CC4=CNC=N4)NC([C@H](CCC(O)=O)NC([C@H](CCSC)N)=O)=O)=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 962.10 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Magrì A, Tabbì G, Giuffrida A, Pappalardo G, Satriano C, Naletova I, Nicoletti VG, Attanasio F. Influence of the N-terminus acetylation of Semax, a synthetic analog of ACTH(4-10), on copper(II) and zinc(II) coordination and biological properties. J Inorg Biochem. 2016 Nov;164:59-69. doi: 10.1016/j.jinorgbio.2016.08.013. Epub 2016 Aug 27. PubMed PMID: 27586814. 2: Mölle M, Pietrowsky R, Fehm HL, Born J. Regulation of human thought by neuropeptide ACTH 4-10: an analysis of the EEG's dimensional complexity. Neuroreport. 1997 Aug 18;8(12):2715-20. PubMed PMID: 9295106. 3: Gruber KA, Callahan MF. ACTH-(4-10) through gamma-MSH: evidence for a new class of central autonomic nervous system-regulating peptides. Am J Physiol. 1989 Oct;257(4 Pt 2):R681-94. Review. PubMed PMID: 2552843. 4: Miller LH, Turnbull BA. The effect of MSH/ACTH 4-10 on delayed response performance and post-test locomotor activity in rats. Peptides. 1986 Mar-Apr;7(2):201-5. PubMed PMID: 3016679.